Mouse Anti-SERPING1 Recombinant Antibody (clone 23H8)
CAT#: MOB-1965z
This product is a mouse antibody that recognizes human SERPING1. It can be used in the following applications: WB, ELISA, IHC, IP.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows strong positivity in plasma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48738/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lung
Immunohistochemical staining of human lung shows strong positivity in plasma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26161/ihc_selected.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26161/57862_A_8_4.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26161/57862_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (ASC diff, ASC TERT1, HSkMC)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149131-SERPING1
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Specifications
- Immunogen
- Human Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human SERPING1
- Species Reactivity
- Human
- Clone
- 23H8
- Applications
- WB, ELISA, IHC, IP
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Immunoprecipitation.
Target
- Alternative Names
- SERPING1; C1IN; Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1; HAE2; C1 Inh; Serine (Or Cysteine) Proteinase Inhibitor, Clade G (C1 Inhibitor), Member 1, (Angioedema, Hereditary); C1NH; Plasma Protease C1 Inhibitor; Serpin G1; Angioedema; C
- UniProt ID
- P05155
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Worked for IP
Successfully used this anti-SERPING1 antibody (clone 23H8) for Immunoprecipitation (IP) from human cell lysates. The antibody performed well, and we were able to confirm its pulldown by Western Blot, for which this antibody is also validated. It's a solid mouse IgG2a.
Multi-App Validation
It's great to find an antibody with broad validation. We've used clone 23H8 for both ELISA and IHC. The performance is reliable across these applications. This is a very useful tool for our research into the complement system, allowing us to use one antibody for different assays.
Q&As
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What is the isotype of MOB-1965z and what applications can it be used for?
A: This is a mouse monoclonal antibody of the IgG2a isotype, and its clone name is 23H8. It has been validated for a robust set of applications, including Western Blot (WB), ELISA, Immunohistochemistry (IHC), and Immunoprecipitation (IP). It is specified to react with human SERPING1.
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My research involves the complement cascade. Can you tell me more about this antibody's target?
A: Certainly. This antibody targets SERPING1, which is also widely known in research as C1 inhibitor. It is a critical serine protease inhibitor (serpin) that regulates the complement and coagulation pathways. This antibody, clone 23H8, is an excellent tool for studying the role of this protein in human biological systems.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "SERPING1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0950MZ | Recombinant Mouse Anti-Human SERPING1 Antibody (clone N92) | ELISA, FuncS, ICC, IF, IHC-Fr, IHC-P, IP, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3227 | Hi-Affi™ Recombinant Rabbit Anti-SERPING1 Monoclonal Antibody (DS3227AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1367 | AbPlus™ Anti-SERPING1 Magnetic Beads (VS-0724-YC1367) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1050 | Rabbit Anti-SERPING1 Recombinant Antibody (VS13-YC1050) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2038 | Anti-SERPING1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6498 | Anti-Mouse SERPING1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6497 | Anti-Human SERPING1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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