Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) (CAT#: Gly-157LC)
This product is a non-fucosylated chimeric (primate/human) monoclonal antibody. The antibody with enhanced ADCC specficfically binds to human CD23 and can be potentially used in the treatment of chronic lymphocytic leukemia.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
Figure 2 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Figure 4 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
Glyco-engineering
- Glycosylation site
- Fc region
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- CD23 (Cluster of differentiation-23)
- Host Species
- Human
- Derivation
- Chimeric (primate/human)
- Type
- Chimeric antibody (primate/human)
- Specificity
- Human
- Applications
- ELISA
Target
- Alternative Names
- FCER2; Fc fragment of IgE receptor II; CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2
- Related Disease
- Chronic lymphocytic leukemia
- Gene ID
- 2208
- UniProt ID
- P06734
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1377z | Mouse Anti-FCER2 Recombinant Antibody (clone 31H8) | WB, ELISA, IF, IHC | Mouse IgG2a |
| MOB-0281MZ | Recombinant Mouse Anti-Human Fc fragment of IgE, low affinity II, receptor for (CD23) Antibody (clone NHM7) | IHC | Mouse antibody |
| HPAB-1148-FY | Human Anti-FCER2 Recombinant Antibody (HPAB-1148-FY) | Activ | Human IgG |
| HPAB-1149-FY | Monkey Anti-FCER2 Recombinant Antibody (HPAB-1149-FY) | Activ | Monkey IgG |
| VS3-XY3355 | Rabbit Anti-FCER2 Recombinant Antibody (clone R08-8A1) | WB, IHC-P, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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