Recombinant Anti-FCER2 Vesicular Antibody, EV Displayed (VS-0425-YC203) (CAT#: VS-0425-YC203)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• FCER2

• Host Animal
• Human

• Antibody Isotype
• IgG1

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Fc epsilon receptor II

• Molecular Function
• IgE-binding protein, Receptor

• Introduction
• The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

• Alternative Names
• CD23, CD23A, CLEC4J, FCE2, FcepsilonRII, FCErII

• Gene ID
• 2208

• UniProt ID
• P06734

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