Recombinant Anti-FCER2 Vesicular Antibody, EV Displayed (VS-0425-YC203)
CAT#: VS-0425-YC203
The Recombinant Anti-FCER2 Vesicular Antibody, EV Displayed (VS-0425-YC203) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FCER2-expressed cells or tissues. The FCER2 is a low-affinity receptor for IgE, promoting B-cell growth and IgE regulation. It exists as a secreted mitogenic growth factor. Variants encoding different isoforms have been described.
Gene Expression
Normal Tissue
Figure 1 High expression in lymph node
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
Normal Tissue
Figure 2 Low expression in endometrium 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
Normal Tissue
Figure 3 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
❮
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FCER2
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Fc epsilon receptor II
- Molecular Function
- IgE-binding protein, Receptor
- Introduction
- The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Alternative Names
- CD23, CD23A, CLEC4J, FCE2, FcepsilonRII, FCErII
- Gene ID
- 2208
- UniProt ID
- P06734
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| NEUT-787CQ | Mouse Anti-FCER2 Recombinant Antibody (clone TU1) | FC, IHC-Fr, ICC, WB, Block | Mouse IgG3, κ |
| NEUT-789CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL329) | ELISA, WB, Block, CyTOF®, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
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| MOR-1268 | Hi-Affi™ Rabbit Anti-FCER2 Recombinant Antibody (clone DS1268AB) | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| AFC-TAB-231 | Afuco™ Anti-FCER2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-231) | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-F(E) | Human Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1148-FY-F(E)) | Activ | Human Fab |
| HPAB-1149-FY-F(E) | Monkey Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1149-FY-F(E)) | Activ | Monkey Fab |
| HPAB-0530-YJ-S(P) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); scFv Fragment | ELISA, IHC | Mouse scFv |
| HPAB-0531-YJ-S(P) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); scFv Fragment | ELISA, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1148-FY-S(P)) | Activ | Monkey scFv |
| HPAB-1149-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1149-FY-S(P)) | Activ | Monkey scFv |
| HPAB-0530-YJ-F(E) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); Fab Fragment | ELISA, IHC | Mouse Fab |
| HPAB-0531-YJ-F(E) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); Fab Fragment | ELISA, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0859F | Mouse Anti-FCER2 Recombinant Antibody (clone LVNC-4) | FC | Mouse IgG1 |
| ZG-0996F | Mouse Anti-FCER2 Recombinant Antibody (clone 5E3) | FC | Mouse IgG1 |
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| VS3-CJ449 | Mouse Anti-FCER2 Recombinant Antibody (VS3-CJ449) | WB, IHC | Mouse IgG |
| VS3-CJ450 | Mouse Anti-FCER2 Recombinant Antibody (clone EBVCS-5) | IF, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
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| VS-0225-XY111 | CytoStream™ Mouse Anti-FCER2 Recombinant Antibody (clone EBVCS-5) | FC | Mouse IgG1, kappa |
| VS13-YC385 | CytoStream™ Rabbit Anti-FCER2 Recombinant Antibody (VS13-YC385) | IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY83 | Human Anti-FCER2 (clone 1E9) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2478 | Anti-FCER2 Immunohistochemistry Kit | IHC |
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