Recombinant Mouse Anti-Human CLEC6A Antibody (clone JNH4E2)

CAT#: MOB-1082MZ

This antibody is a recombinant mouse monoclonal antibody which specifically reacts with human CLEC6A.

Gene Expression
Figure 1 RNA cell line category: Cell line enriched (NTERA-2)

Specifications

  • Immunogen
  • Synthetic peptide, corresponding to amino acids 75-125 of Human DECTIN 2 (Q6EIG7)
  • Host Species
  • Mouse
  • Type
  • Mouse antibody
  • Antibody Isotype
  • IgG3
  • Specificity
  • Human CLEC6A
  • Species Reactivity
  • Human
  • Clone
  • JNH4E2
  • Applications
  • FC, WB

Target

  • Alternative Names
  • CLEC6A; Human CLEC6A
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Breast cancer biomarkers at key points during disease progression
Investigating Dectin-2
We used the Recombinant Anti-Human CLEC6A Antibody to study the expression of Dectin-2 on dendritic cells. The antibody worked very well in flow cytometry, showing a distinct shift in fluorescence intensity on positive cells. It helped us phenotype our immune cell populations accurately. The recombinant quality ensures low batch variation, which is essential for our comparative studies.
Breast cancer biomarkers at key points during disease progression
Innate Immunity Marker
This antibody is a reliable marker for CLEC6A in our innate immunity research. We utilized it for immunohistochemistry on human tonsil tissue, and it specifically stained the relevant myeloid cell subsets. The signal was strong and localization was correct. It has been a valuable addition to our panel of antibodies for studying C-type lectin receptors and fungal recognition pathways.

Q&As

  1. What is the common name for the target CLEC6A, and what cells express it?

    A: CLEC6A is more commonly known as Dectin-2. It is a C-type lectin receptor primarily expressed on the surface of myeloid cells, including dendritic cells and macrophages. It plays a key role in antifungal immunity. This antibody is an excellent tool for identifying these cell populations and studying Dectin-2 signaling in your research.

  2. Is this antibody suitable for flow cytometry on human cells?

    A: Yes, this Recombinant Anti-Human CLEC6A Antibody is suitable for Flow Cytometry. It is designed to bind to the extracellular domain of Dectin-2 on live or fixed cells. We recommend it for phenotyping human immune cells to assess Dectin-2 expression levels under various experimental conditions.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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