Recombinant Human Anti-human AMICA1 Antibody (CAT#: MHH-58)
Recombinant Human Antibody recognizes and binds to Human AMICA1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-AMICA1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-AMICA1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5854/1954_D11_31_cr5dfb7ddd913c7_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5854/1954_D11_31_cr5dfb7ddd913c7_selected.jpg
Figure 2 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/ihc_selected.jpg
(Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_B_9_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_B_9_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_A_9_3.jpg
Figure 5 Testis
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_A_6_6.jpg
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47919/110784_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160593-JAML
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160593-JAML
Specifications
- Immunogen
- Human adhesion molecule, interacts with CXADR antigen 1
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human adhesion molecule, interacts with CXADR antigen 1
- Species Reactivity
- Human
- Applications
- Products can be used for: Western blot; Flow Cytometry; Functional Study
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- AMICA1; adhesion molecule, interacts with CXADR antigen 1; JAML; AMICA; Gm638; CREA7-1; CREA7-4; junctional adhesion molecule-like; adhesion molecule AMICA; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4; adhesion molecul
- Gene ID
- 120425
- UniProt ID
- B3KUI3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-58 | Recombinant Anti-human AMICA1 Antibody | WB, IF, FuncS | IgG |
| PABL-252 | Hamster Anti-AMICA1 Recombinant Antibody (clone HL4E10) | WB, ELISA, FuncS | Hamster IgG, λ |
| TAB-0608CL | Mouse Anti-AMICA1 Recombinant Antibody (TAB-0608CL) | Inhib, FC, IF, ELISA | Mouse IgG2a |
| TAB-0610CL | Mouse Anti-AMICA1 Recombinant Antibody (TAB-0610CL) | Inhib, FC, ELISA | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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