Recombinant Human Anti-human IMMT Antibody
CAT#: MHH-571
Recombinant Human Antibody exhibits selective binding affinity to Human IMMT, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IMMT mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IMMT mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36165/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in renal tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_A_7_3.jpg
Normal Tissue
Figure 6 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_A_8_4.jpg
Normal Tissue
Figure 7 Testis
Preleptotene spermatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_A_6_6.jpg
Normal Tissue
Figure 8 Heart muscle
Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_B_6_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36164/124713_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000132305-IMMT
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Specifications
- Immunogen
- Human inner membrane protein, mitochondrial
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human inner membrane protein, mitochondrial
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Flow Cytometry; Enzyme-linked Immunosorbent Assay; Functional Study
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- IMMT; inner membrane protein, mitochondrial; HMP; P87; P89; PIG4; PIG52; MINOS2; P87/89; MICOS complex subunit MIC60; mitofilin; motor protein; proliferation-inducing gene 4; mitochondrial inner membrane protein; cell proliferation-inducing protein 52; ce
- Gene ID
- 10989
- UniProt ID
- Q16891
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IMMT"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-571 | Recombinant Anti-human IMMT Antibody | WB, IHC, FuncS | IgG |
| MOB-1927MZ | Recombinant Mouse Anti-Human IMMT Antibody (clone 3F5BE6) | FC, ICC, IF, IHC-P, IP, ELISA, WB | Mouse antibody |
| VS3-FY756 | Recombinant Rabbit Anti-IMMT Antibody (clone R03-6H5) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-571-F(E) | Recombinant Anti-human IMMT Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| MHH-571-F(E) | Recombinant Human Anti-human IMMT Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-571-S(P) | Recombinant Anti-human IMMT Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| MHH-571-S(P) | Recombinant Human Anti-human IMMT Antibody scFv Fragment | FC, Neut, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1823 | Rabbit Anti-IMMT Recombinant Antibody (clone DS1823AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1124 | Anti-IMMT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3551 | Anti-Mouse IMMT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3550 | Anti-Human IMMT Immunohistochemistry Kit | IHC |
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