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IMMT
Loading...Anti-IMMT Products
- Recombinant Anti-human IMMT Antibody (MOB-571)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FuncS
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, ICC/IF, IHC-P, IP, ELISA, WB
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- Recombinant Human Anti-human IMMT Antibody scFv Fragment (MHH-571-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, Neut, Biosensors, FuncS
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- Recombinant Anti-human IMMT Antibody scFv Fragment (MOB-571-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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- Recombinant Anti-human IMMT Antibody Fab Fragment (MOB-571-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, IF, FuncS
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- Recombinant Human Anti-human IMMT Antibody Fab Fragment (MHH-571-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IP, FuncS
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- Anti-Mouse IMMT Immunohistochemistry Kit (VS-0525-XY3551)
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- Species Reactivity: Human, Mouse, Rat
- Target: IMMT
- Application: IHC
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- Anti-IMMT Immunohistochemistry Kit (VS-0325-XY1124)
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- Species Reactivity: Human, Mouse, Rat
- Target: IMMT
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
IMMT (Inner Membrane Mitochondrial Protein) is a Protein Coding gene. Diseases associated with IMMT include Gracile Syndrome and Melanoma-Associated Retinopathy.
Protein class
Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MICOS10/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and MICOS13/MIC13 (PubMed:25764979, 25781180). This complex was also known under the names MINOS or MitOS complex. The MICOS complex associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2 (together described as components of the mitochondrial outer membrane sorting assembly machinery (SAM) complex) and DNAJC11, mitochondrial inner membrane protein TMEM11 and with HSPA9 (PubMed:25764979, 25781180). The MICOS and SAM complexes together with DNAJC11 are part of a large protein complex spanning both membranes termed the mitochondrial intermembrane space bridging (MIB) complex (PubMed:22252321). Interacts with HSPA1A/HSPA1B and OPA1, preferentially with the soluble OPA1 form (By similarity). Interacts with MICOS13/MIC13, MICOS10/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, SAMM50 and TMEM11 (PubMed:25997101). Interacts with APOO/MIC23/MIC26 and APOOL/MIC27 (PubMed:25764979, 25781180). Interacts with ARMC1 (PubMed:31644573). Interacts with ARMC12 (By similarity). (Microbial infection) Interacts with human cytomegalovirus protein UL13; this interaction alters cristae architecture.
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