Recombinant Mouse Anti-Testosterone Antibody Fab Fragment (77Fab)
CAT#: PABX-176-F (E)
Anti-Testosterone antibody is a Mouse of Fab class that binds to an Testosterone.
Published Data
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Figure 1 Overlay plot of the subtractive sensograms obtained after sequential injection of the wt 3-C4F5 and 77 Fab fragments
over a CM5 sensor chip surface containing immobilized testoserone-3-CMO-BSA.
Overlay plot of the subtractive sensograms obtained after sequential injection of the wt 3-C4F5 and 77 Fab fragments
over a CM5 sensor chip surface containing immobilized testoserone-3-CMO-BSA.
Valjakka, J., Hemminki, A., Niemi, S., Söderlund, H., Takkinen, K., & Rouvinen, J. (2002). Crystal Structure of an in Vitro Affinity-and Specificity-matured Anti-testosterone Fab in Complex with Testosterone IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS. Journal of Biological Chemistry, 277(46), 44021-44027.
-2.png)
Figure 2 Structure of the variable domain of 77 Fab in complex with testosterone (blue).
The mutations of the 77 Fab are shown in red. The figure has been drawn by the SETOR program.
Valjakka, J., Hemminki, A., Niemi, S., Söderlund, H., Takkinen, K., & Rouvinen, J. (2002). Crystal Structure of an in Vitro Affinity-and Specificity-matured Anti-testosterone Fab in Complex with Testosterone IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS. Journal of Biological Chemistry, 277(46), 44021-44027.
-3.png)
Figure 3 The binding site in the 77 Fab (A) and in the wt Fab (B) structures.
The solvent-accessible surface was produced using the O program.
Valjakka, J., Hemminki, A., Niemi, S., Söderlund, H., Takkinen, K., & Rouvinen, J. (2002). Crystal Structure of an in Vitro Affinity-and Specificity-matured Anti-testosterone Fab in Complex with Testosterone IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS. Journal of Biological Chemistry, 277(46), 44021-44027.
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fab
- Specificity
- Tested positive against native Testosterone
- Clone
- 77Fab
- Applications
- Neut (assay dependent)
FuncS (assay dependent)
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- Testosterone; (8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta phenanthren-3-one; Androderm; Delatestryl; testred; TESTOSTERONE; testex; testoderm
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 77Fab"
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-100 | Recombinant Anti-human Testosterone VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-963-S(P) | Recombinant Human Anti-Testosterone Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| PSBC-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C(4)F(5)); scFv Fragment | WB, FuncS | Mouse scFv |
| PSBZ-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5); scFv Fragment | Block | Mouse scFv |
| PSBC-121 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5 mutant (77)); scFv Fragment | WB, ELISA | Mouse scFv |
| FAMAB-0283-YC-S(P) | Human Anti-Testosterone Recombinant Antibody (clone TC-5); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C(4)F(5)) | WB, FuncS | Mouse IgG |
| PABZ-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5) | Block | Mouse IgG |
| PABC-121 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5 mutant (77)) | WB, ELISA | Mouse IgG |
| MOB-0213MZ | Recombinant Mouse Anti-Testosterone Antibody (clone A7004) | ELISA | Mouse antibody |
| FAMAB-0283YC | Human Anti-Testosterone Recombinant Antibody (clone TC-5) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C(4)F(5)); Fab Fragment | WB, FuncS | Mouse Fab |
| PFBZ-120 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5); Fab Fragment | Block | Mouse Fab |
| PFBC-121 | Mouse Anti-Testosterone Recombinant Antibody (clone 3-C4F5 mutant (77)); Fab Fragment | WB, ELISA | Mouse Fab |
| FAMAB-0301-CN-F(E) | Human Anti-Testosterone Recombinant Antibody (clone TM-7); Fab Fragment | ELISA | Human Fab |
| FAMAB-0302-CN-F(E) | Human Anti-Testosterone Recombinant Antibody (clone TM-4); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-176 | Recombinant Mouse Anti-Testosterone Antibody (77Fab) | Neut, FuncS | IgG |
| PABX-176-S (P) | Recombinant Mouse Anti-Testosterone Antibody scFv Fragment (77Fab) | Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-YC1857 | DrugMonitor™ Rabbit Anti-Testosterone Antibody (VS-0125-YC1857) | ELISA, Lateral Flow, PK/PD, ADA Control | Rabbit IgG |
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