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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    SH3 domain scaffold protein anti-Human Pyk2 (CAT#: SST-L190)

    The SH3 domain that bound Pyk2 was isolated from the library using Yeast Two-hybrid techonology. After affinity maturation, SH3 domain variants were identified having affinities for Pyk2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3850/624_D4_2_selected.jpg
    Figure 2 IHC staining of human cerebral cortex
    Figure 2 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/ihc_selected.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_8_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Nuclear
    Hepatocytes
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Nuclear
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_4_6.jpg
    Figure 8 Tonsil
    Figure 8 Tonsil
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear
    Squamous epithelial cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_6_8.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26091/58711_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (Daudi, REH)
    Figure 10 RNA cell line category: Cell line enhanced (Daudi, REH)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000120899-PTK2B/subcellular

    Specifications

    • Scaffold Name
    • SH3 domain
    • Origin
    • PSD-95 protein
    • Target
    • Pyk2
    • Species Reactivity
    • Human
    • Expression Host
    • E. coli
    • Applications
    • ELISA; IHC; Microscopy; FC; WB; FuncS

    Target

    • Alternative Names
    • PSD-95 protein; SH3 domain; CADTK; CAKB; FADK2; FAK2; PKB; PTK; PYK2; RAFTK

    Downloads

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    MOB-1616z Mouse Anti-PTK2B Recombinant Antibody (clone 27C3) WB, ELISA, IHC Mouse IgG2a
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    VS3-QX937 Mouse Anti-PTK2B Recombinant Antibody (clone 4B4-D0-F3) WB, IHC, ICC, FC, ELISA Mouse IgG2a
    VS7-0425-WR713 Mouse Anti-PTK2B Monoclonal Antibody (VS7-0425-WR713) WB, IHC-P, IF, ELISA Mouse IgG
    VS7-0425-WR714 Mouse Anti-PTK2B Recombinant Antibody (VS7-0425-WR714) WB Mouse IgG

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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