Scorpion toxins scaffold protein anti-HIV-1 gp120

CAT#: SSX-L184

The Scorpion toxin that bound gp120 was isolated from the library using Phage display techonology. After affinity maturation, Scorpion toxins variants were identified having affinities (KD=8 nM) for gp120 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Specifications

  • Scaffold Name
  • Scorpion toxins
  • Origin
  • Scorpion toxins
  • Core Structure
  • α/β3 (25-40)
  • Variable Regions
  • Loop grafting or 4 aa
  • Target
  • gp120
  • Species Reactivity
  • HIV-1
  • Expression Host
  • E. coli
  • Affinity Constant
  • 8 nM

Target

  • Alternative Names
  • Scorpion toxins; Scorpion toxins; HIV1gp8
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