PE-A*02:01/Human EVI-1 (MILDEFYNV) MHC Tetramer (CAT#: MHC-CN0200)
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
Figure 2 High expression in breast
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (HEL, HMC-1, JURKAT)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- EVI-1
- Antigen Species
- Human
- Peptide
- MILDEFYNV
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Alternative Names
- RUNX1; PEA2-Alpha B; AML1-EVI-1 Fusion Protein; CBF-Alpha-2; EVI-1; Runt-Related Transcription Factor 1; Aml1 Oncogene; PEBP2aB
- Gene ID
- 861
- UniProt ID
- Q01196
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2922z | Mouse Anti-RUNX1 Recombinant Antibody (clone 24G12) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MRO-1351-CN | Recombinant Rabbit Anti-RUNX1 Monoclonal Antibody (CBACN-491) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-077R | Mouse Anti-RUNX1 Recombinant Antibody (ZG-077R) | WB, ELISA | Mouse IgG |
| ZG-078R | Mouse Anti-RUNX1 Recombinant Antibody (ZG-078R) | WB, ELISA | Mouse IgG |
| VS3-WK840 | Rabbit Anti-RUNX1 Recombinant Antibody (VS3-WK840) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
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