Recombinant Mouse anti-Human RUNX1 Monoclonal antibody (FQ2566Z) (CAT#: MOB-2284CT)
Recombinant Mouse Monoclonall antibody to Human RUNX1, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/if_selected.jpg
Figure 2 High expression in breast
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12282_B_3_4_val_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4176/12382_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (HEL, HMC-1, JURKAT)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159216-RUNX1
Specifications
- Immunogen
- A synthetic peptide from internal part of human, rat and mouse RUNX1 / AML1 conjugated to an immunogenic carrier protein
- Host Species
- Mouse
- Specificity
- Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
- Species Reactivity
- Human
- Clone
- FQ2566Z
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Western Blot; Immunohistochemistry paraffin embedded sections; Immunohistochemistry (Frozen sections)
- Conjugate
- Unconjugated
Product Property
- Purity
- Whole antiserum
- Format
- Lyophilised :Reconstitute in 100 μl of sterile water. Centrifuge to remove any insoluble material.
- Buffer
- Preservative: None. Constituents: Whole serum
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- RUNX1; runt-related transcription factor 1; AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; CBF-alpha-2; PEA2-alpha B; PEBP2-alpha B; oncogene AML-1; AML1-EVI-1 fusion protein; acute myeloid leukemia 1 protein; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; core-binding factor, runt domain, alpha subunit 2; polyomavirus enhancer-binding protein 2 alpha B subunit;
- Gene ID
- 861
- UniProt ID
- Q01196
- Protein Refseq
- NP_001001890
- Function
- ATP binding; DNA binding; DNA binding; calcium ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription f
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "RUNX1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3142 | Hi-Affi™ Recombinant Rabbit Anti-RUNX1 Monoclonal Antibody (DS3142AB) | WB, IHC-P | IgG |
| MOR-4728 | Hi-Affi™ Recombinant Rabbit Anti-RUNX1 Monoclonal Antibody (TH242DS) | WB | IgG |
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