APC-A*02:01/Human GRIK2 (ALMRQGSEL) MHC Tetramer

CAT#: MHC-CN0019

Gene Expression
Figure 1 IHC staining of human hippocampus Figure 2 Cerebral cortex Figure 3 Cerebellum Figure 4 Colon Figure 5 Kidney Figure 6 Testis Figure 7 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HAP1, SiHa, WM-115)

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • GRIK2
  • Antigen Species
  • Human
  • Peptide
  • ALMRQGSEL
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • GRIK2; BA487F5.1; Glutamate Receptor 6; Glutamate Receptor Ionotropic, Kainate 2; Glutamate Receptor Form E; GLR6; GLUK6; Glutamate Receptor, Ionotropic, Kainate 2
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