PE-A*24:02/Human BCL2A1 (DYLQYVLQI) MHC Tetramer
CAT#: MHC-CN0421
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140379-BCL2A1
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Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- BCL2A1
- Antigen Species
- Human
- Peptide
- DYLQYVLQI
- Conjugate
- PE
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Alternative Names
- BCL2 Related Protein A1; Hemopoietic-Specific Early Response Protein; Bcl-2-Like Protein 5; Protein BFL-1; Bcl2-L-5; BCL2L5; HBPA1; BFL1; GRS;
- Gene ID
- 597
- UniProt ID
- Q16548
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Related Signaling Pathways
p53 Signaling Pathway
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Protocol & Troubleshooting
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See other products for "BCL2A1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0343 | Hi-Affi™ Rabbit Anti-BCL2A1 Recombinant Antibody (clone DS343AB) | WB, FC, IP, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0162-CN | Rabbit Anti-BCL2A1 Recombinant Antibody (clone CBACN-063) | WB, IHC, FC | Rabbit IgG |
| VS3-WK1007 | Rabbit Anti-BCL2A1 Recombinant Antibody (VS3-WK1007) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0422 | APC-A*24:02/Human BCL2A1 (DYLQYVLQI) MHC Tetramer | FCM, IHC | |
| MHC-CN0423 | FITC-A*24:02/Human BCL2A1 (DYLQYVLQI) MHC Tetramer | FCM, IHC | |
| MHC-CN0424 | A*24:02/Human BCL2A1 (DYLQYVLQI) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY730 | Anti-BCL2A1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY731 | Anti-Mouse BCL2A1 Immunohistochemistry Kit | IHC |
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