AbPlus™ Anti-AIFM1 Magnetic Beads (VS-0724-YC1250)
CAT#: VS-0724-YC1250
The AbPlus Anti-AIFM1 Magnetic Beads (VS-0724-YC1250) is an innovative affinity resin which is bound with anti-AIFM1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of AIFM1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30611/1912_B2_32_selected.jpg
Normal Tissue
Figure 2 Kidney
Bowman's capsule Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3764/10710_A_9_5.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3764/10710_A_5_6.jpg
Normal Tissue
Figure 4 Adrenal gland
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3764/10710_B_4_5.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3764/10710_A_9_4.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000156709-AIFM1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-AIFM1 specific antibody
- Target
- AIFM1
- Immunogen
- Recombinant human AIFM1/AIF fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
- Alternative Names
- Apoptosis Inducing Factor Mitochondria Associated 1; Apoptosis-Inducing Factor, Mitochondrion-Associated, 1; Programmed Cell Death 8 (Apoptosis-Inducing Factor); PDCD8; AIF; Neuropathy, Axonal, Motor-Sensory With Deafness And Mental Retardation (Cowchock Syndrome); Apoptosis Inducing Factor, Mitochondria Associated 1; Apoptosis-Inducing Factor 1, Mitochondrial; Striatal Apoptosis-Inducing Factor; Testicular Secretory Protein Li 4;
- Gene ID
- 9131
- UniProt ID
- O95831
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "AIFM1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0112 | Hi-Affi™ Rabbit Anti-AIFM1 Recombinant Antibody (clone DS112AB) | WB, IP, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MRO-0038-CN | Rabbit Anti-AIFM1 Recombinant Antibody (clone CBACN-014) | WB, IF, IHC, IP, FC | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY9 | AbPlus™ Anti-AIFM1 Magnetic Beads (VS-0424-XY9) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
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| VS-0325-XY67 | Anti-AIFM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY244 | Anti-Mouse AIFM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY243 | Anti-Human AIFM1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC35 | CytoStream™ Rabbit Anti-AIFM1 Recombinant Antibody (VS13-YC35) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
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