Can this antibody be used for inhibition assays?

Yes, this Recombinant Human Antibody recognizes ANGPTL3 and is validated for Inhibition (Inhib) assays and ELISA. It binds to ANGPTL3, a protein involved in lipid metabolism and angiogenesis control.

What is the affinity of this antibody?

The antibody has a KD of 17.5 nM. It is purified by affinity chromatography and shows greater than 95% purity by SDS-PAGE. It specifically reacts with the epitope of human ANGPTL3.

Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0221-FY)

CAT#: HPAB-0221-FY

This product is a recombinant antibody that recognizes Human ANGPTL3. The monoclonal antibody reacts with the epitope of ANGPTL3. ANGPTL3 is contemplated by the expression control to control blood sugar, and inhibition of tumor angiogenesis.

Gene Expression

Normal Tissue Figure 1 IHC staining of human liver

Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78355_B_9_5.jpg

Normal Tissue Figure 3 Colon

Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_3.jpg

Normal Tissue Figure 4 Liver

Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_9_4.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_4_6.jpg

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Specifications

Host Species
Human

Type
Human IgG

Specificity
Human ANGPTL3

Species Reactivity
Human

Applications
ELISA, Inhib

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Angiopoietin Like 3; Angiopoietin 5; ANGPT5; ANG-5; Angiopoietin-Related Protein 3; Angiopoietin-Like Protein 3

Gene ID
27329

UniProt ID
Q9Y5C1

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Q&As

Can this antibody be used for inhibition assays?

A: Yes, this Recombinant Human Antibody recognizes ANGPTL3 and is validated for Inhibition (Inhib) assays and ELISA. It binds to ANGPTL3, a protein involved in lipid metabolism and angiogenesis control.
What is the affinity of this antibody?

A: The antibody has a KD of 17.5 nM. It is purified by affinity chromatography and shows greater than 95% purity by SDS-PAGE. It specifically reacts with the epitope of human ANGPTL3.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0221-FY.pdf

MSDS

MSDS - HPAB-0221-FY.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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TAB-0902CLV	Mouse Anti-ANGPTL3 Recombinant Antibody (TAB-0902CLV)	ELISA, Neut, FuncS	Mouse IgG1

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HPAB-0187-FY	Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY)	Inhib	Human IgG4, κ

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HPAB-0187-FY-S(P)	Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-S(P)); scFv Fragment	Inhib	Human scFv

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HPAB-0187-FY-F(E)	Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-F(E)); Fab Fragment	Inhib	Human Fab

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HPAB-0222-FY	Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0222-FY)	ELISA, Inhib	Human IgG

CAT	Product Name	Application	Type
HPAB-0221-FY-S(P)	Human Anti-ANGPTL3 Recombinant Antibody scFv Fragment (HPAB-0221-FY-S(P))	ELISA, Inhib	Human scFv

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HPAB-0222-FY-S(P)	Human Anti-ANGPTL3 Recombinant Antibody scFv Fragment (HPAB-0222-FY-S(P))	ELISA, Inhib	Human scFv

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HPAB-0221-FY-F(E)	Human Anti-ANGPTL3 Recombinant Antibody Fab Fragment (HPAB-0221-FY-F(E))	ELISA, Inhib	Human Fab

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HPAB-0222-FY-F(E)	Human Anti-ANGPTL3 Recombinant Antibody Fab Fragment (HPAB-0222-FY-F(E))	ELISA, Inhib	Human Fab

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VS-0723-WK210	Rabbit Anti-ANGPTL3 Recombinant Antibody (VS-0723-WK210)	ELISA, FC	Rabbit IgG

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VS-0525-XY376	Anti-Mouse ANGPTL3 Immunohistochemistry Kit	IHC

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