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ANGPTL3

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For Research Use Only. Not For Clinical Use.


Background

ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism. ANGPTL3 monoclonal antibody recognizes the fibrinogen-like domain (FLD) of human ANGPTL3. It detects a band of ~68 kDa and a cleaved band of ~35 kDa by WB. It does not cross-react with other ANGPTL family proteins.
ANGPTL3
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Hepatocytes, Proximal tubular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts with ANGPTL8. Interacts with ITGB3 (By similarity).

Molecular function

Heparin-binding

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