AbPlus™ Anti-ANTXR1 Magnetic Beads (VS-0424-XY14)

CAT#: VS-0424-XY14

The AbPlus Anti-ANTXR1 Magnetic Beads (VS-0424-XY14) is an innovative affinity resin which is bound with anti-ANTXR1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ANTXR1 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line HeLa Figure 2 RNA cell line category: Cell line enhanced (LHCN-M2, TIME)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-ANTXR1 specific antibody
  • Target
  • ANTXR1
  • Target Species
  • Human, Mouse
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
  • Alternative Names
  • ATR; GAPO; TEM8; anthrax toxin receptor 1; 2310008J16Rik; 2810405N18Rik; tumor endothelial marker 8
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See other products for "ANTXR1"

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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