Recombinant Anti-ANTXR1 Vesicular Antibody, EV Displayed (VS-0425-YC116) (CAT#: VS-0425-YC116)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ANTXR1

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• ANTXR cell adhesion molecule 1

• Molecular Function
• Receptor

• Cellular Localization
• Vesicles

• Introduction
• Predicted to enable actin filament binding activity; collagen binding activity; and transmembrane signaling receptor activity. Acts upstream of or within blood vessel development; negative regulation of extracellular matrix assembly; and positive regulation of metallopeptidase activity. Predicted to be located in external side of plasma membrane; filopodium membrane; and lamellipodium membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in several structures, including brain; chondrocranium; costal cartilage; immune system; and liver. Human ortholog(s) of this gene implicated in GAPO syndrome and colorectal carcinoma. Orthologous to human ANTXR1 (ANTXR cell adhesion molecule 1).

• Alternative Names
• Tem8; Antrx1; 2310008J16Rik; 2810405N18Rik

• Gene ID
• 69538

• UniProt ID
• Q505H2

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