Recombinant Anti-ANTXR1 Vesicular Antibody, EV Displayed (VS-0425-YC116)
CAT#: VS-0425-YC116
The Recombinant Anti-ANTXR1 Vesicular Antibody, EV Displayed (VS-0425-YC116) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ANTXR1-expressed cells or tissues. The ANTXR1 is associated with actin filament and collagen binding, as well as transmembrane signaling receptor activity. It plays a role in blood vessel development, extracellular matrix assembly regulation, and metallopeptidase activity, and is located on various membranes including the plasma membrane. ANTXR1 is expressed in tissues such as the brain, cartilage, immune system, and liver, with human orthologs linked to GAPO syndrome and colorectal carcinoma.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54785/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169604-ANTXR1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ANTXR1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- ANTXR cell adhesion molecule 1
- Molecular Function
- Receptor
- Cellular Localization
- Vesicles
- Introduction
- Predicted to enable actin filament binding activity; collagen binding activity; and transmembrane signaling receptor activity. Acts upstream of or within blood vessel development; negative regulation of extracellular matrix assembly; and positive regulation of metallopeptidase activity. Predicted to be located in external side of plasma membrane; filopodium membrane; and lamellipodium membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in several structures, including brain; chondrocranium; costal cartilage; immune system; and liver. Human ortholog(s) of this gene implicated in GAPO syndrome and colorectal carcinoma. Orthologous to human ANTXR1 (ANTXR cell adhesion molecule 1).
- Alternative Names
- Tem8; Antrx1; 2310008J16Rik; 2810405N18Rik
- Gene ID
- 69538
- UniProt ID
- Q505H2
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Datasheet
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COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-583CT-S(P) | Human Anti-ANTXR1 Recombinant Antibody; scFv Fragment (TAB-583CT-S(P)) | ELISA, FC, IHC, IF | Human scFv |
| TAB-584CT-S(P) | Humanized Anti-ANTXR1 Recombinant Antibody; scFv Fragment (TAB-584CT-S(P)) | ELISA, FC, IHC, IF | Humanized scFv |
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| TAB-586CT-S(P) | Humanized Anti-ANTXR1 Recombinant Antibody; scFv Fragment (TAB-586CT-S(P)) | ELISA, FC, IHC, IF | Humanized scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0006-YC | Human Anti-ANTXR1 Recombinant Antibody (clone T802) | ELISA, FC | Humanized IgG |
| HPAB-M0007-YC | Human Anti-ANTXR1 Recombinant Antibody (clone T803) | ELISA, FC | Humanized IgG |
| HPAB-M0008-YC | Human Anti-ANTXR1 Recombinant Antibody (clone T801) | ELISA, FC | Humanized IgG |
| HPAB-0253-YJ | Human Anti-ANTXR1 Recombinant Antibody (HPAB-0253-YJ) | IP, FC, IF, FuncS | Human IgG1 |
| HPAB-0254-YJ | Human Anti-ANTXR1 Recombinant Antibody (HPAB-0254-YJ) | FC, Inhib | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0006-YC-S(P) | Human Anti-ANTXR1 Recombinant Antibody (clone T802); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-M0007-YC-S(P) | Human Anti-ANTXR1 Recombinant Antibody (clone T803); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-M0008-YC-S(P) | Human Anti-ANTXR1 Recombinant Antibody (clone T801); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0253-YJ-S(P) | Human Anti-ANTXR1 Recombinant Antibody; scFv Fragment (HPAB-0253-YJ-S(P)) | FuncS | Human scFv |
| HPAB-0254-YJ-S(P) | Human Anti-ANTXR1 Recombinant Antibody; scFv Fragment (HPAB-0254-YJ-S(P)) | FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0006-YC-F(E) | Human Anti-ANTXR1 Recombinant Antibody (clone T802); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-M0007-YC-F(E) | Human Anti-ANTXR1 Recombinant Antibody (clone T803); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-M0008-YC-F(E) | Human Anti-ANTXR1 Recombinant Antibody (clone T801); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0253-YJ-F(E) | Human Anti-ANTXR1 Recombinant Antibody; Fab Fragment (HPAB-0253-YJ-F(E)) | FuncS | Human Fab |
| HPAB-0254-YJ-F(E) | Human Anti-ANTXR1 Recombinant Antibody; Fab Fragment (HPAB-0254-YJ-F(E)) | FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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