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ANTXR1
Anti-ANTXR1 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, IF, Funcs, Inhib, IHC, ELISA, Cyt
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- Human Anti-ANTXR1 Antibody, mRNA (TAB-043CL-mRNA)
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- Species Reactivity: Human
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- Human Anti-ANTXR1 Antibody (clone T802), mRNA (HPAB-M0006-YC-mRNA)
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- Species Reactivity: Human
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- Human Anti-ANTXR1 Antibody (clone T803), mRNA (HPAB-M0007-YC-mRNA)
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- Species Reactivity: Human
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- Human Anti-ANTXR1 Antibody (clone T801), mRNA (HPAB-M0008-YC-mRNA)
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- Species Reactivity: Human
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- AbPlus™ Anti-ANTXR1 Magnetic Beads (VS-0424-XY14) (VS-0424-XY14)
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- Target: ANTXR1
- Target Species: Human, Mouse
- Application: IP, Protein Purification
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- Human Anti-ANTXR1 Recombinant Antibody (HPAB-0253-YJ) (HPAB-0253-YJ)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: IP, FC, IF, FuncS
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- Human Anti-ANTXR1 Recombinant Antibody (HPAB-0254-YJ) (HPAB-0254-YJ)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, Inhib
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- Human Anti-ANTXR1 Recombinant Antibody (clone T801) (HPAB-M0008-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Humanized Fab
- Application: ELISA, FC, IHC, IF
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- Human Anti-ANTXR1 Recombinant Antibody (clone T802) (HPAB-M0006-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody (clone T803) (HPAB-M0007-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Humanized Fab
- Application: ELISA, FC, IHC, IF
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA, FC, IHC, IF
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA, FC, IHC, IF
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Human IgG1
- Application: ELISA, FC, IHC, IF
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- Derivation: Humanized
- Species Reactivity: Mouse
- Type: Human IgG1
- Application: ELISA, FC, IHC, IF
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- Anti-Human ANTXR1 Recombinant Antibody (TAB-043CL)
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- Species Reactivity: Human
- Type: Antibody
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- Human Anti-ANTXR1 Recombinant Antibody (clone T802); scFv Fragment (HPAB-M0006-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody (clone T803); scFv Fragment (HPAB-M0007-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody (clone T801); scFv Fragment (HPAB-M0008-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody (clone T802); Fab Fragment (HPAB-M0006-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody (clone T803); Fab Fragment (HPAB-M0007-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody; scFv Fragment (HPAB-0253-YJ-S(P)) (HPAB-0253-YJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FuncS
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- Human Anti-ANTXR1 Recombinant Antibody; scFv Fragment (HPAB-0254-YJ-S(P)) (HPAB-0254-YJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FuncS
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- Human Anti-ANTXR1 Recombinant Antibody; Fab Fragment (HPAB-0253-YJ-F(E)) (HPAB-0253-YJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FuncS
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- Human Anti-ANTXR1 Recombinant Antibody (clone T801); Fab Fragment (HPAB-M0008-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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- Human Anti-ANTXR1 Recombinant Antibody; Fab Fragment (HPAB-0254-YJ-F(E)) (HPAB-0254-YJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FuncS
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For Research Use Only. Not For Clinical Use.
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Astrocytes, Skeletal myocytes, Endometrial stromal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (LHCN-M2, TIME)
Interaction
Interacts with gelatin and type 1 collagen. Interacts with the actin cytoskeleton. (Microbial infection) Interacts (via VWFA domain) with the protective antigen (PA) of B.anthracis (PubMed:11700562, PubMed:12700348, PubMed:16762926, PubMed:20585457). Binding does not occur in the presence of calcium (PubMed:11700562, PubMed:12700348, PubMed:16762926, PubMed:20585457).
Molecular function
Receptor
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