Rabbit Anti-ARG1 Recombinant Antibody (clone R02-1J9)
CAT#: VS3-XY3267
This is a recombinant rabbit antibody that recognizes human ARG1 (Arginase 1), which is a key element of the urea cycle converting L-arginine to urea and L-ornithine. The antibody recognizes and binds to human ARG1. It also has cross-reactivity against mouse or rat ARG1. This antibody has been used in Western Blot and Immunoprecipitation.
Gene Expression
Normal Tissue
Figure 1 High expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3595/10647_A_8_4_val_selected.jpg
Normal Tissue
Figure 2 Low expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3595/10647_A_3_3_val_selected.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80011/171017_A_7_4.jpg
Normal Tissue
Figure 4 Bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80011/171017_B_6_4.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HL-60)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118520-ARG1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat ARG1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-1J9
- Applications
- WB, IP
- Related Disease
- Argininemia; Autoimmune Hepatitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IP: 1/20
Target
- Gene ID
- 383
- UniProt ID
- P05089
- Long Name
- Arginase 1
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P05089)
Modification sites at neXtProt (NX_P05089)
Glycosylation from GlyGen (P05089) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001231367.1; NP_000036.2
- Function
- Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ARG1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0686MZ | Chicken Anti-ARG1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0238 | Hi-Affi™ Rabbit Anti-ARG1 Recombinant Antibody (clone DS238AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0790-YJ | Mouse Anti-ARG1 Recombinant Antibody (CBA84D) | FC, IA | Mouse IgG1 |
| MOB-0793-YJ | Mouse Anti-ARG1 Recombinant Antibody (CBA87D) | IHC-Fr, IA, IP | Mouse IgG1 |
| ZG-0036J | Mouse Anti-ARG1 Recombinant Antibody (ZG-0036J) | IHC-P, IF | Mouse IgG |
| ZG-0037J | Mouse Anti-ARG1 Recombinant Antibody (ZG-0037J) | IHC-P, IF | Mouse IgG |
| VS3-CJ388 | Mouse Anti-ARG1 Recombinant Antibody (clone ABT-Arg1) | WB, IHC-P | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY18 | AbPlus™ Anti-ARG1 Magnetic Beads (JB21-49) | IP, Protein Purification | |
| VS-0724-YC1258 | AbPlus™ Anti-ARG1 Magnetic Beads (VS-0724-YC1258) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY153 | Anti-ARG1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY498 | Anti-Mouse ARG1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY497 | Anti-Human ARG1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY499 | Anti-Rat ARG1 Immunohistochemistry Kit | IHC |
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