AbPlus™ Anti-Ascl1 Magnetic Beads (VS-0724-YC1216) (CAT#: VS-0724-YC1216)
The AbPlus Anti-Ascl1 Magnetic Beads (VS-0724-YC1216) is an innovative affinity resin which is bound with anti-Ascl1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of Ascl1 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg

Figure 2 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg

Figure 3 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg

Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg

Figure 5 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-Ascl1 specific antibody
- Target
- Ascl1
- Immunogen
- Synthetic peptide corresponding to the center region of the mouse MASH1/ASCL1.
- Target Species
- Mouse, Rat
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
- Alternative Names
- ASH1, Mash1, bHLHa46
- Gene ID
- 17172
Downloads
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IgG Antibodies
IHC Kits & Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1209CT | Mouse Anti-ASCL1 Recombinant Antibody (clone EML200) | WB | Mouse IgG2a |
VS13-YC70 | Rabbit Anti-ASCL1 Recombinant Antibody (VS13-YC70) | IHC-P | Rabbit IgG |
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