AbPlus™ Anti-Ascl1 Magnetic Beads (VS-0724-YC1216)
CAT#: VS-0724-YC1216
The AbPlus Anti-Ascl1 Magnetic Beads (VS-0724-YC1216) is an innovative affinity resin which is bound with anti-Ascl1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of Ascl1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
Normal Tissue
Figure 2 High expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-Ascl1 specific antibody
- Target
- Ascl1
- Immunogen
- Synthetic peptide corresponding to the center region of the mouse MASH1/ASCL1.
- Target Species
- Mouse, Rat
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
- Alternative Names
- ASH1, Mash1, bHLHa46
- Gene ID
- 17172
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ASCL1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1209CT | Mouse Anti-ASCL1 Recombinant Antibody (clone EML200) | WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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| VS13-YC70 | Rabbit Anti-ASCL1 Recombinant Antibody (VS13-YC70) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0525-XY548 | Anti-ASCL1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY549 | Anti-Mouse ASCL1 Immunohistochemistry Kit | IHC |
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