Mouse Anti-ATXN1 Recombinant Antibody (clone 4C7B11)

Name: Mouse Anti-ATXN1 Recombinant Antibody (clone 4C7B11)
SKU: VS7-HM182
Rating: 5 (1 reviews)

CAT#: VS7-HM182

Mouse Anti-ATXN1 Recombinant Antibody (clone 4C7B11) is an mouse IgG1 antibody that recognizes the Human, Mouse, Rat, Monkey ATXN1 by WB, IHC, FCM.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line RT4

Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70756/1385_C12_2_selected.jpg

Normal Tissue Figure 2 IHC staining of human cerebral cortex

Immunohistochemical staining of human cerebral cortex shows strong nuclear and cytoplasmic positivity in neuronal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/ihc_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_B_8_5.jpg

Normal Tissue Figure 4 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_A_9_3.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_A_9_4.jpg

Normal Tissue Figure 6 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_A_7_5.jpg

Normal Tissue Figure 7 Testis

Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_A_4_6.jpg

Normal Tissue Figure 8 Lymph node

Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8335/22386_A_9_8.jpg

RNA Expression Figure 9 RNA cell line category: Cell line enhanced (U-266/70)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124788-ATXN1

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Specifications

Immunogen
Purified recombinant human ATXN1 (AA: 645-815) fragment expressed in E. Coli.

Host Species
Mouse

Derivation
Mouse

Type
Mouse IgG1

Specificity
Human, Mouse, Rat, Monkey ATXN1

Species Reactivity
Human, Mouse, Rat, Monkey

Clone
4C7B11

Applications
WB, IHC, FCM

Conjugate
None

Product Property

Clonality
Monoclonal

Purification
Affinity-chromatography

Format
Liquid

Molecular Weight
86.9kDa

Concentration
Please refer to the tube label.

Buffer
PBS

Preservative
0.05% sodium azide.

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Ice pack

Target

Alternative Names
ATXN1; D6S504E; Ataxin 1; SCA1; Spinocerebellar Ataxia Type 1 Protein; Ataxin-1; ATX1; Spinocerebellar Ataxia 1 (Olivopontocerebellar Ataxia 1, Autosomal Dominant, Ataxin 1)

UniProt ID
P54253

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS7-HM182.pdf

MSDS

MSDS - VS7-HM182.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

CAT
Product Name

Recommended Dilution Buffer

CAT
Product Name

See other products for "ATXN1"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-4056z	Mouse Anti-ATXN1 Recombinant Antibody (clone 44G3)	WB, IP, IF, ELISA	Mouse IgG1, κ
MOB-0694MZ	Mouse Anti-ATXN1 Recombinant Antibody (clone 3G6)	ELISA, IF, WB	Mouse IgG1
VS-0422-LC25	Mouse Anti-ATXN1 Recombinant Antibody (clone mN76/8)	IP, WB, IHC	Mouse IgG2a
VS7-HM181	Mouse Anti-ATXN1 Recombinant Antibody (clone 2B8A2)	WB, FCM	Mouse IgG1
VS7-HM183	Mouse Anti-ATXN1 Recombinant Antibody (clone CBL059HM)	WB, IHC-p, IF, ICC, FCM, ELISA	Mouse IgG

CAT	Product Name	Application	Type
VS-0525-XY652	Anti-ATXN1 Immunohistochemistry Kit	IHC
VS-0525-XY653	Anti-Mouse ATXN1 Immunohistochemistry Kit	IHC

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