Rabbit Anti-BGN Recombinant Antibody (clone R07-4G6)
CAT#: VS3-XY3277
The antibody is a recombinant rabbit antibody against BGN (Biglycan), which may be involved in collagen fiber assembly. The molecular weight of this antibody is about 42 kDa. It specifically reacts with human, mouse and rat BGN. This product has been reported for use in Western Blot, Immunoprecipitation and Flow cytometry.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3157/1742_D5_7_cr5804956327650_selected.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_5.jpg
Normal Tissue
Figure 4 High expression in placenta
Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_3_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182492-BGN
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat BGN
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-4G6
- Applications
- WB, IP, FC
- Related Disease
- Meester-Loeys syndrome (MRLS)
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IP: 1/20
FC: 1/50-1/100
Target
- Alternative Names
- PGI; MRLS; DSPG1; PG-S1; SEMDX; SLRR1A
- Gene ID
- 633
- UniProt ID
- P21810
- Long Name
- Biglycan
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
- Protein Refseq
- XP_054183538.1; XP_016885213.1
- Function
- May be involved in collagen fiber assembly.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
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Secondary Antibody
- CAT
- Product Name
See other products for "BGN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2941z | Mouse Anti-BGN Recombinant Antibody (clone 18G12) | WB, ELISA, IHC, IP | Mouse IgG2a, κ |
| MOB-2268MZ | Mouse Anti-BGN Recombinant Antibody (clone CBLS-199) | FC, IF, IHC-P, WB | Mouse IgG2a |
| MRO-0180-CN | Rabbit Anti-BGN Recombinant Antibody (clone JB71-31) | WB, IHC, FC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0354 | Hi-Affi™ Rabbit Anti-BGN Recombinant Antibody (clone DS354AB) | WB, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY239 | Anti-BGN Immunohistochemistry Kit | IHC | |
| VS-0525-XY762 | Anti-Human BGN Immunohistochemistry Kit | IHC |
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