Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone 7C1) (CAT#: FAMAB-0120WJ)
This product is a mouse monoclonal antibody targeting C. botulinum BoNT/A1 and BoNT/A2 derived from phage display library. This antibody can be used in applications, such as ELISA, WB, IP, Neut.
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ELISA
Figure 1 Binding of BoNT/A monoclonal antibodies to BoNT/A1 and BoNT/A2 toxins as determined by capture ELISA.
Wells were coated with the indicated MAb followed by various concentrations of pure or complex BoNT/A1 or BoNT/A2. Toxin binding was detected using polyclonal equine BoNT/A antisera.
Smith, T. J., Lou, J., Geren, I. N., Forsyth, C. M., Tsai, R., Laporte, S. L., Tepp, W. H., Bradshaw, M., Johnson, E. A., Smith, L. A., & Marks, J. D. (2005). Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization. Infection and immunity, 73(9), 5450–5457.
Specifications
- Immunogen
- Recombinant BoNT/A1 C-terminal heavy chain (HC) and boosted with BoNT/A1 toxin
- Host Species
- Mouse
- Derivation
- Phage Display Library
- Type
- Mouse IgG1, κ
- Specificity
- C. botulinum BoNT/A1 and BoNT/A2
- Species Reactivity
- C. botulinum
- Clone
- 7C1
- Applications
- ELISA, WB, Neut
- Related Disease
- C. botulinum
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Botulinum neurotoxin type A; BoNT/A
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Single Domain Antibody Products
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1537-sdAb | Recombinant Anti-C. botulinum BoNT/A VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
| HPAB-0684-YJ-VHH | Camelid Anti-C. botulinum BoNT/A Recombinant Single Domain Antibody (HPAB-0684-YJ-VHH) | ELISA, Neut | Camelid VHH |
| HPAB-0685-YJ-VHH | Camelid Anti-C. botulinum BoNT/A Recombinant Single Domain Antibody (HPAB-0685-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
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