Mouse Anti-CAPN2 Recombinant Antibody (VS3-CJ717) (CAT#: VS3-CJ717)
This product is a mouse antibody that recognizes human, and rat CAPN2.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/if_selected.jpg
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows moderate positivity in subsets of urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/ihc_selected.jpg
(Immunohistochemical staining of human urinary bladder shows moderate positivity in subsets of urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_7_5.jpg
Figure 4 Bronchus
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_5_2.jpg
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_5_2.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_A_8_5.jpg
Figure 6 RNA cell line category: Cell line enhanced (TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162909-CAPN2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162909-CAPN2
Specifications
- Immunogen
- KLH-conjugated synthetic peptide between amino acids from the human region of human CAPN2
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human, Rat CAPN2
- Species Reactivity
- Human, Rat
- Applications
- WB, IHC-P, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.3.
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:1000), Immunohistochemistry-Parraffin (1:25), Flow Cytometry (1:100).
Target
- Alternative Names
- CANP2; mCANP; CANPL2; CANPml
- Gene ID
- 824
- UniProt ID
- P17655
- Sequence Similarities
- Belongs to the peptidase C2 family.
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane
- Protein Refseq
- NP_001139540.1; NP_001739.2
- Function
- Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508).
Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "CAPN2"
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IgG Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2088z | Mouse Anti-CAPN2 Recombinant Antibody (clone 3B9) | ELISA, WB | Mouse IgG1 |
| MRO-0217-CN | Rabbit Anti-CAPN2 Recombinant Antibody (clone JA43-41) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-QX151 | Mouse Anti-CAPN2 Recombinant Antibody (clone 1381CT669.7.66.71) | WB, IHC, FC | Mouse IgG2b |
| VS4-WK59 | Rabbit Anti-CAPN2 Recombinant Antibody (clone 17E9) | ELISA, WB | Rabbit IgG |
| VS3-FY2643 | Mouse Anti-CAPN2 Recombinant Antibody (VS3-FY2643) | WB, IHC, FC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
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