Rabbit Anti-CD24 Antibody (VS-0924-YC23) - Cancer Stem Cell Marker
CAT#: VS-0924-YC23
This product is an anti-CD24 antibody (VS-0924-YC23) that specifically targets the human CD24 protein, known as a marker for cancer stem cells (CSCs). It's suitable for detecting CD24 in CSC tissues or cells through Immunofluorescence at a concentration of 0.5-2 µg/mL.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45879/1529_A2_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/1725_B2_2_selected.jpg
Normal Tissue
Figure 3 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows strong membranous positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_B_5_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_A_8_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_A_9_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/78471/168061_A_4_6.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (NTERA-2, RPTEC TERT1, RT4, SK-BR-3)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000272398-CD24
❮
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CD24
- Species Reactivity
- Human
- Applications
- IF
- Related Disease
- Multiple Sclerosis
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity purified using the PrEST antigen as affinity ligand
- Concentration
- 0.05 mg/mL
- Buffer
- PBS, pH 7.2, with 40% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunofluorescence (IF): 0.5-2 µg/mL
Target
- Alternative Names
- CD24 Molecule; CD24 Antigen (Small Cell Lung Carcinoma Cluster 4 Antigen); CD24A; Small Cell Lung Carcinoma Cluster 4 Antigen; Signal Transducer CD24; CD24 Antigen
- Gene ID
- 100133941
- Long Name
- CD24 molecule
- Sequence Similarities
- Belongs to the CD24 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Extensively O-glycosylated. (P25063-CD24_HUMAN)
Glycosylation at Asn36 and Asn52 (NX_P25063 [NX_P25063-1])
Glycosylation from GlyConnect CD24_HUMAN (1086)
Glycosylation from GlyGen (P25063) 3 sites, 13 N-linked glycans (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_054209946.1; NP_001278666.1; NP_001278667.1; NP_001278668.1; NP_001346013.1
- Function
- May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CD24"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-006LC | Mouse Anti-CD24 Recombinant Antibody (TAB-006LC) | FC, FuncS | Mouse IgG2a |
| TAB-006LC-S(P) | Mouse Anti-CD24 Recombinant Antibody; scFv Fragment (TAB-006LC-S(P)) | FC | Mouse scFv |
| TAB-006LC-F(E) | Mouse Anti-CD24 Recombinant Antibody; Fab Fragment (TAB-006LC-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-007LC | Human Anti-CD24 Recombinant Antibody (TAB-007LC) | FC | Humanized antibody |
| TAB-007LC-S(P) | Human Anti-CD24 Recombinant Antibody; scFv Fragment (TAB-007LC-S(P)) | FC | Humanized scFv |
| TAB-007LC-F(E) | Human Anti-CD24 Recombinant Antibody; Fab Fragment (TAB-007LC-F(E)) | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0434-CN | Mouse Anti-CD24 Recombinant Antibody (clone E4) | WB, ELISA, Neut | Mouse IgG1, κ |
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| VS-0723-WK207 | Human Anti-CD24 Recombinant Antibody (VS-0723-WK207) | ELISA, FC | Chimeric (rabbit/human) IgG1 |
| VS-0723-WK217 | Human Anti-CD24 Recombinant Antibody (VS-0723-WK217) | ELISA, FC | Chimeric (rabbit/human) IgG1 |
| VS3-FY2151 | Rabbit Anti-CD24 Recombinant Antibody (clone R69-1X-8) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0434-CN-S(P) | Mouse Anti-CD24 Recombinant Antibody (clone E4); scFv Fragment | WB, ELISA, Neut | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0433-CN-F(E) | Mouse Anti-CD24 Recombinant Antibody Fab Fragment | WB, ELISA, Neut | Mouse Fab |
| HPAB-0434-CN-F(E) | Mouse Anti-CD24 Recombinant Antibody (clone E4); Fab Fragment | WB, ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY27 | CytoStream™ Mouse Anti-CD24 Recombinant Antibody (VS-0225-XY27) | FC | Mouse IgG2a, kappa |
| VS-0225-XY26 | CytoStream™ Mouse Anti-CD24 Recombinant Antibody (VS-0225-XY26) | FC | Mouse IgM, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1145 | Anti-CD24 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1146 | Anti-Mouse CD24 Immunohistochemistry Kit | IHC |
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