Rabbit Anti-CDCA5 Recombinant Antibody (clone R05-8H3) (CAT#: VS3-XY3306)
This product is a recombinant rabbit antibody targeting the CDCA5 (Cell division cycle associated 5), which is a regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. It recognizes and binds to human CDCA5. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Flow cytometry, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin, Flow cytometry and Immunofluorescence is 1/500-1/1000, 1/50-1/100, 1/50-1/100 and 1/50-1/200, respectively.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CDCA5
- Species Reactivity
- Human
- Clone
- R05-8H3
- Applications
- WB, IHC-P, ICC, IF, FC
- Related Disease
- Roberts-Sc Phocomelia Syndrome; Cornelia De Lange Syndrome
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
FC: 1/50-1/100
Target
- Alternative Names
- SORORIN
- Gene ID
- 113130
- UniProt ID
- Q96FF9
- Long Name
- Cell division cycle associated 5
- Cellular Localization
- Chromosome, Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the inhibition of WAPL by CDCA5.
Ubiquitinated by the APC/C complex in G1, leading to its degradation.
- Protein Refseq
- XP_005273790.1
- Function
- Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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