Mouse Anti-CDKN1C Recombinant Antibody (clone PT0208) (CAT#: VS3-CJ1003)
This product is a mouse antibody that recognizes human CDKN1C.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/32_C5_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/32_C5_1_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_B_8_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_B_8_5.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_8_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_4_6.jpg
Figure 5 Placenta
(Decidual cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_1_7.jpg
(Decidual cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_1_7.jpg
Figure 6 RNA cell line category: Cell line enhanced (EFO-21, HeLa, RPMI-8226, SH-SY5Y, SiHa, SK-MEL-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129757-CDKN1C
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129757-CDKN1C
Specifications
- Immunogen
- Synthesized peptide derived from human p57kip2
- Host Species
- Mouse
- Type
- Mouse IgG3, κ
- Specificity
- Human CDKN1C
- Species Reactivity
- Human
- Clone
- PT0208
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- BWS; WBS; p57; BWCR; KIP2; p57Kip2
- Gene ID
- 1028
- UniProt ID
- P49918
- Sequence Similarities
- Belongs to the CDI family.
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_000067.1; NP_001116102.1; NP_001116103.1
- Function
- Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1514CT | Recombinant Mouse anti-Human CDKN1C Monoclonal antibody (4F4) | ELISA, WB | |
| MOB-0160F | Mouse Anti-CDKN1C Recombinant Antibody (MOB-0160F) | IHC-P, IF | Mouse IgG |
| MOB-0161F | Mouse Anti-CDKN1C Recombinant Antibody (MOB-0161F) | IHC-P, IF | Mouse IgG |
| MOB-0162F | Mouse Anti-CDKN1C Recombinant Antibody (MOB-0162F) | WB | Mouse IgG |
| VS3-XY480 | Mouse Anti-CDKN1C Recombinant Antibody (clone 3E3) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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