Recombinant Anti-CGRP (AA 90-100 x Phe109/119) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC211)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human CALCA (αCGRP) and CALCB (βCGRP)

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Epitope 1
• aa 90-100, VTHRLAGLLSR

• Epitope 2
• C-terminal region where Phe109 and Phe119 are key contributors

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, IHC, FC, IP, IF, Inhib

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Calcitonin Gene-Related Peptide

• Introduction
• This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• CALCA; calcitonin related polypeptide alpha; CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I

• Gene ID
• 796

• UniProt ID
• P01258

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