AbPlus™ Anti-CHRM2 Magnetic Beads (P90-131) (CAT#: VS-0424-XY65)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-CHRM2 specific antibody (P90-131)

• Target
• CHRM2

• Target Species
• Human

• Antibody Clone
• P90-131

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

• Alternative Names
• Cholinergic Receptor, Muscarinic 2; Acetylcholine Receptor, Muscarinic 2; Acetylcholine Receptor; Muscarinic M2 Receptor; Muscarinic 2; 7TM Receptor; HM2

• Gene ID
• 1129

• UniProt ID
• P08172

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