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  • Rabbit Anti-CITED2 Recombinant Antibody (clone R01-2G8)

Rabbit Anti-CITED2 Recombinant Antibody (clone R01-2G8) (CAT#: VS3-XY3316)

This antibody is a recombinant rabbit antibody targeting the CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2), which regulates TGF-beta signaling. It specifically reacts with human and mouse CITED2. It has been reported for use in Western Blot. The recommended dilutions of Western Blot is 1/500-1/1000.


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  • Datasheet
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  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16157/951_E5_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human duodenum
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16157/ihc_selected.jpg
Figure 3 IHC staining of human rectum
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_4_3_selected.jpg
Figure 4 Lymph node
Figure 4 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_9_8.jpg
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_B_7_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_7_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_7_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_9_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Peritubular cells Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_5_6.jpg
Figure 10 Ovary
Figure 10 Ovary
(Ovarian stroma cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69879/154942_A_6_7.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (BJ, fHDF/TERT166)
Figure 11 RNA cell line category: Cell line enhanced (BJ, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164442-CITED2

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Mouse CITED2
  • Species Reactivity
  • Human, Mouse
  • Clone
  • R01-2G8
  • Applications
  • WB
  • Related Disease
  • Atrial Septal Defect 8; Ventricular Septal Defect 2

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000

Target

  • Alternative Names
  • ASD8; MRG1; VSD2; MRG-1; P35SRJ
  • Long Name
  • Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
  • Cellular Localization
  • Nucleus
  • Post Translation Modifications
  • Modification sites at PhosphoSitePlus (Q99967)
    Modification sites at neXtProt (NX_Q99967)
  • Function
  • Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity.

Recommended Products

Isotype Control

Recommended Dilution Buffer

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CITED2"

Recombinant Antibody

CAT Product Name Application Type
MOB-2246MZ Recombinant Mouse Anti-Human CITED2 Antibody (clone KB33) WB Mouse antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0706 Hi-Affi™ Rabbit Anti-CITED2 Recombinant Antibody (clone DS706AB) WB, IP Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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