Human Anti-Citrullinated epitope Recombinant Antibody (clone F12); scFv Fragment (CAT#: HPAB-AP044-YC-S(P))
Autoimmune reactions to certain epitopes of self antigens most likely contribute to the development of rheumatoid arthritis. Often these epitopes are citrullinated. Provided are novel antibodies that can bind to certain citrullinated epitopes namely citrullinated enolase, vimentin, fibrinogen and citrullinated synthetic peptides. The antibody may also be an antibody that binds to only CCP, cit-fib and cit-vim such as antibody F12. The antibody can be used in diagnostics of rheumatoid arthritis, for therapy against rheumatoid arthritis and as research tools.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human Citrullinated epitope
- Species Reactivity
- Human
- Clone
- F12
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP042-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone A40) | ELISA | Human IgG |
| HPAB-AP043-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone C07) | ELISA | Human IgG |
| HPAB-AP044-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone F12) | ELISA | Human IgG |
| HPAB-AP045-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone 109) | ELISA | Human IgG |
| HPAB-AP605-YC | Mouse Anti-Citrullinated epitope Recombinant Antibody (HPAB-AP605-YC) | ELISA, IHC, WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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