Human Anti-CLDN18.2 Recombinant Antibody (HPAB-AP289-YC)
CAT#: HPAB-AP289-YC
This product is a recombinant chimeric (human/mouse) antibody that recognizes CLDN18.2, a unique molecule for targeted therapy in different cancers. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (Mouse/Human)
- Type
- Chimeric (Mouse/Human) IgG1, κ
- Specificity
- Human CLDN18.2
- Species Reactivity
- Human
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Claudin 18.2
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Targets Gastric Cancer Marker
We are researching Claudin 18.2 as a target for gastric cancer therapy. This recombinant chimeric antibody (Human/Mouse) binds specifically to CLDN18.2. It has been an essential control in our ELISA assays for validating the expression of this tight junction protein on differentiated gastric epithelial cells.
Consistent Chimeric Antibody
The quality of this antibody is excellent, with SDS-PAGE confirming>95% purity. We appreciate the chimeric IgG1 format, which allows us to use anti-human secondary antibodies for detection. It has been stable at 4°C for our short-term experiments and stores well at -20°C for longer periods.
Q&As
-
Is this antibody specific for the CLDN18.2 isoform?
A: Yes, this recombinant chimeric antibody recognizes CLDN18.2 (Claudin 18.2), which is a stomach-specific isoform of Claudin-18. CLDN18.2 is a unique molecule often displayed on the surface of human gastric cancer cells, making it a key target for therapy research.
-
What is the species composition of this chimeric antibody?
A: This is a Chimeric (Mouse/Human) antibody. It contains a Mouse variable region and a Human IgG1, kappa constant region. It is expressed in mammalian cells and purified by affinity chromatography to>95% purity.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CLDN18.2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-0120-YJ) | ELISA, WB, IHC-P | Mouse IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0121-YJ | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-0121-YJ) | ELISA, WB, IHC-P | Mouse IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-0120-YJ-S(P)) | ELISA, WB, IHC-P | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0121-YJ-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-0121-YJ-S(P)) | ELISA, WB, IHC-P | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0120-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0121-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0121-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP280-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP280-YC) | ELISA | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP281-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP281-YC) | ELISA | Mouse IgG3, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP282-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP282-YC) | ELISA | Mouse IgG3, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP280-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP280-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP281-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP281-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP282-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP282-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP280-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP280-YC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP281-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP281-YC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP282-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP282-YC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY88 | Human Anti-CLDN18.2 scFv-Fc Chimera (VS-0325-FY88) | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC80 | SmartAb™ Recombinant Anti-CLDN18.2 pH-dependent Antibody (VS-0825-YC80) | ELISA, WB, IHC-P | Mouse IgG kappa |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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