Human Anti-CLDN18.2 scFv-Fc Chimera (VS-0325-FY88)
CAT#: VS-0325-FY88
The anti-CLDN18.2 scFv-Fc antibody targets claudin-18 splice variant 2, a protein overexpressed in certain gastrointestinal cancers. It is designed to deliver targeted therapy to CLDN18.2-positive cells, enhancing the specificity of cancer treatments. The scFv-Fc format provides high affinity and prolonged circulation time, improving its therapeutic potential.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CLDN18.2
- Species Reactivity
- Human
- Applications
- Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Claudin 18; Surfactant Associated Protein J; Surfactant, Pulmonary Associated Protein J; Surfactant Associated 5; Claudin-18; SFTA5; SFTPJ
- Long Name
- Claudin 18
- Function
- CLDN18.2 (Claudin 18 isoform 2) is a tight junction protein predominantly expressed in gastric mucosa and is often overexpressed in gastric cancer. It's a target for cancer therapy, as it plays a key role in maintaining epithelial barrier function.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CLDN18.2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-0120-YJ) | ELISA, WB, IHC-P | Mouse IgG, κ |
| HPAB-0121-YJ | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-0121-YJ) | ELISA, WB, IHC-P | Mouse IgG, κ |
| HPAB-AP280-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP280-YC) | ELISA | Mouse IgG2a, κ |
| HPAB-AP281-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP281-YC) | ELISA | Mouse IgG3, κ |
| HPAB-AP282-YC | Mouse Anti-CLDN18.2 Recombinant Antibody (HPAB-AP282-YC) | ELISA | Mouse IgG3, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-0120-YJ-S(P)) | ELISA, WB, IHC-P | Mouse scFv |
| HPAB-0121-YJ-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-0121-YJ-S(P)) | ELISA, WB, IHC-P | Mouse scFv |
| HPAB-AP280-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP280-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP281-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP281-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP282-YC-S(P) | Mouse Anti-CLDN18.2 Recombinant Antibody; scFv Fragment (HPAB-AP282-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0120-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| HPAB-0121-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0121-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| HPAB-AP280-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP280-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP281-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP281-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP282-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP282-YC-F(E)) | ELISA | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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