Human Anti-CLDN18.2 scFv-Fc Chimera (VS-0325-FY88) (CAT#: VS-0325-FY88)
The anti-CLDN18.2 scFv-Fc antibody targets claudin-18 splice variant 2, a protein overexpressed in certain gastrointestinal cancers. It is designed to deliver targeted therapy to CLDN18.2-positive cells, enhancing the specificity of cancer treatments. The scFv-Fc format provides high affinity and prolonged circulation time, improving its therapeutic potential.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CLDN18.2
- Species Reactivity
- Human
- Applications
- Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Claudin 18; Surfactant Associated Protein J; Surfactant, Pulmonary Associated Protein J; Surfactant Associated 5; Claudin-18; SFTA5; SFTPJ
- Long Name
- Claudin 18
- Function
- CLDN18.2 (Claudin 18 isoform 2) is a tight junction protein predominantly expressed in gastric mucosa and is often overexpressed in gastric cancer. It's a target for cancer therapy, as it plays a key role in maintaining epithelial barrier function.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0120-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0120-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| HPAB-0121-YJ-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-0121-YJ-F(E)) | ELISA, WB, IHC-P | Mouse Fab |
| HPAB-AP280-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP280-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP281-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP281-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP282-YC-F(E) | Mouse Anti-CLDN18.2 Recombinant Antibody; Fab Fragment (HPAB-AP282-YC-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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