Mouse Anti-CLDN3 Recombinant Antibody (clone PT1687)
CAT#: VS3-CJ144
This product is a mouse antibody that recognizes CLDN3.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/1661_D5_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_B_8_5.jpg
Normal Tissue
Figure 3 Small intestine
Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%
Paneth cells
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_4_2.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Collecting ducts
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_9_5.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (MCF7, PC-3, RPMI-8226, SCLC-21H, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165215-CLDN3
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Specifications
- Immunogen
- Synthesized peptide derived from human Claudin 3
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human CLDN3
- Species Reactivity
- Human
- Clone
- PT1687
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; Hrvp1; RVP1
- Gene ID
- 1365
- UniProt ID
- O15551
- Sequence Similarities
- Belongs to the claudin family.
- Cellular Localization
- Cell junction, Cell membrane, Membrane, Tight junction
- Protein Refseq
- NP_001297.1
- Function
- Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0150-LSX-S(P) | Mouse Anti-CLDN3 Recombinant Antibody (clone CDN08); scFv Fragment | ELISA, FC, FC | Mouse scFv |
| HPAB-0151-LSX-S(P) | Mouse Anti-CLDN3 Recombinant Antibody (clone CDN16); scFv Fragment | ELISA, FC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0150-LSX-F(E) | Mouse Anti-CLDN3 Recombinant Antibody (clone CDN08); Fab Fragment | ELISA, FC, FC | Mouse Fab |
| HPAB-0151-LSX-F(E) | Mouse Anti-CLDN3 Recombinant Antibody (clone CDN16); Fab Fragment | ELISA, FC, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0158J | Mouse Anti-CLDN3 Recombinant Antibody (ZG-0158J) | IHC-P, IF | Mouse IgG |
| ZG-0159J | Mouse Anti-CLDN3 Recombinant Antibody (ZG-0159J) | IHC-P, IF | Mouse IgG |
| VS3-CJ143 | Mouse Anti-CLDN3 Recombinant Antibody (clone ABT-CLD3) | WB, IHC | Mouse IgG1, κ |
| VS3-CJ145 | Mouse Anti-CLDN3 Recombinant Antibody (VS3-CJ145) | WB, IHC | Mouse IgG1 |
| VS3-FY2669 | Rabbit Anti-CLDN3 Recombinant Antibody (VS3-FY2669) | WB, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC133 | Recombinant Anti-CLDN3 Vesicular Antibody, EV Displayed (VS-0425-YC133) | Cyt, ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1484 | Anti-CLDN3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1485 | Anti-Human CLDN3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1486 | Anti-Mouse CLDN3 Immunohistochemistry Kit | IHC |
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