Recombinant Human Anti-CMV Antibody (C11)
CAT#: HPAB-AP298-YC
Antibodies reactive against antigenic domain 4 (AD4) (amino acids 121-132 and 344-438) of CMV AD169 envelope glycoprotein B (gB) were isolated from the plasma of a healthy volunteer having CMV- neutralizing activity. The anti-human cytomegalovirus antibody (C11) has high affinity to CMV with KD value of 5.67 nM. It can be used in the research of treatment, prophylaxis, detection, and diagnosis of human cytomegalovirus infection.
Published Data
IB
Figure 1 Immunoblot analysis of proteins precipitated with different MAbs from an HCMV-infected HELF antigen extract using MAb 28-77 as the detecting antibody
Lane 1, proteins precipitated with Mab 9220; 2, proteins precipitated with MAb CMV-C10; 3, proteins precipitated with MAb CMV-C 11.
Grefte, J. M. M., Van der Gun, B. T. F., Schmolke, S., Van der Giessen, M., Van Son, W. J., Plachter, B., & Jahn, G. (1992). The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during an active cytomegalovirus infection. Journal of General Virology, 73(11), 2923-2932.
IF
Figure 2 Determination of the specificity of MAb CMV-C11 by transient transfection experiments using pp65-RSV and indirect immunofluorescence.
Determination of the specificity of MAb CMV-C11 by transient transfection experiments using pp65-RSV and indirect immunofluorescence.
Grefte, J. M. M., Van der Gun, B. T. F., Schmolke, S., Van der Giessen, M., Van Son, W. J., Plachter, B., & Jahn, G. (1992). The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during an active cytomegalovirus infection. Journal of General Virology, 73(11), 2923-2932.
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Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- CMV
- Species Reactivity
- CMV
- Clone
- C11
- Applications
- IB, IF, ELISA
Product Property
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles
Applications
- Application Notes
- The CMV antibody has been reported in applications of Immunoblotting, Immunofluorescence, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Human cytomegalovirus; hCMV
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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