Mouse Anti-CNN1 Recombinant Antibody (clone ABT-CALP)
CAT#: VS3-CJ1025
This product is a mouse antibody that recognizes human CNN1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to actin filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/120_G8_1_selected.jpg
Normal Tissue
Figure 2 High expression in smooth muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in skeletal muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/32474_B_1_6_val_selected.jpg
Normal Tissue
Figure 4 Smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/32474_B_5_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, K-562, SuSa, U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000130176-CNN1
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Specifications
- Immunogen
- Synthesized peptide derived from human Calponin-1
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CNN1
- Species Reactivity
- Human
- Clone
- ABT-CALP
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- SMCC; Sm-Calp; HEL-S-14
- Gene ID
- 1264
- UniProt ID
- P51911
- Sequence Similarities
- Belongs to the calponin family.
- Cellular Localization
- Cytoskeleton, Focal adhesion
- Protein Refseq
- NP_001290.2; NP_001295270.1
- Function
- Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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Secondary Antibody
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Recommended Dilution Buffer
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| MRO-1713-CN | Rabbit Anti-CNN1 Polyclonal Antibody (MRO-1713-CN) | IF, IHC, FC | Rabbit IgG |
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| VS3-CJ1026 | Rabbit Anti-CNN1 Recombinant Antibody (VS3-CJ1026) | WB, ICC, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0738 | Hi-Affi™ Rabbit Anti-CNN1 Recombinant Antibody (clone DS738AB) | ELISA | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1552 | Anti-CNN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1553 | Anti-Mouse CNN1 Immunohistochemistry Kit | IHC | |
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