AbPlus™ Anti-CTSD Magnetic Beads (VS-0424-XY74)
CAT#: VS-0424-XY74
The AbPlus Anti-CTSD Magnetic Beads (VS-0424-XY74) is an innovative affinity resin which is bound with anti-CTSD specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CTSD protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_B_8_5.jpg
Normal Tissue
Figure 2 Lung
Macrophages
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_2_4.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells
Staining: Medium
Intensity: Moderate
Enterocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, hTERT-RPE1, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117984-CTSD
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-CTSD specific antibody
- Target
- CTSD
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
- Alternative Names
- Cathepsin D; EC 3.4.23.5; CPSD; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D (Lysosomal Aspartyl Protease); Ceroid-Lipofuscinosis, Neuronal 10; Lysosomal Aspartyl Peptidase; Lysosomal Aspartyl Protease; Ceroid-Lipofuscinosis; Neuronal 10; HEL-S-130P; CLN10
- Gene ID
- 1509
- UniProt ID
- P07339
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CTSD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1052 | Mouse Anti-CTSD Recombinant Antibody (clone YC031); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0399-CN-F(E) | Human Anti-CTSD Recombinant Antibody; Fab Fragment (HPAB-0399-CN-F(E)) | ELISA, IF, IP, Neut | Human Fab |
| HPAB-0400-CN-F(E) | Human Anti-CTSD Recombinant Antibody; Fab Fragment (HPAB-0400-CN-F(E)) | ELISA, IF, IP, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0867 | Hi-Affi™ Rabbit Anti-CTSD Recombinant Antibody (clone DS867AB) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0399-CN | Human Anti-CTSD Recombinant Antibody (HPAB-0399-CN) | ELISA, IF, IP, Neut | Human IgG1, λ |
| HPAB-0400-CN | Human Anti-CTSD Recombinant Antibody (HPAB-0400-CN) | ELISA, IF, IP, Neut | Human IgG1, λ |
| MRO-1725-CN | Rabbit Anti-CTSD Polyclonal Antibody (MRO-1725-CN) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-1726-CN | Rabbit Anti-CTSD Polyclonal Antibody (MRO-1726-CN) | WB, IHC, FC | Rabbit IgG |
| VS3-XY557 | Mouse Anti-CTSD Recombinant Antibody (clone 3F2C2) | ELISA, WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0399-CN-S(P) | Human Anti-CTSD Recombinant Antibody; scFv Fragment (HPAB-0399-CN-S(P)) | ELISA, IF, IP, Neut | Human scFv |
| HPAB-0400-CN-S(P) | Human Anti-CTSD Recombinant Antibody; scFv Fragment (HPAB-0400-CN-S(P)) | ELISA, IF, IP, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC901 | AbPlus™ Anti-Ctsd Magnetic Beads (VS-0724-YC901) | IP, Protein Purification | |
| VS-0724-YC1036 | AbPlus™ Anti-CTSD Magnetic Beads (VS-0724-YC1036) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1782 | Anti-CTSD Immunohistochemistry Kit | IHC | |
| VS-0525-XY1783 | Anti-Mouse CTSD Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC79 | Recombinant Anti-CTSD Eliminating Antibody, pH-Sensitive (VS-0625-YC79) | Antigen-Sweeping In Vivo. | Human IgG1 lambda |
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