Rabbit Anti-DGKZ Recombinant Antibody (VS3-FY2689)
CAT#: VS3-FY2689
The anti-DGKZ antibody is a rabbit IgG recombinant monoclonal antibody. It has been specifically designed to target the human DGKZ protein. It cross-reacts with mouse and rat. The monoclonal antibody is suitable for use in Western Blot, Immunoprecipitation assays.
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Diacylglycerol kinase zeta of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IP
- Conjugate
- Unconjugated, FITC
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Target
- Alternative Names
- Diacylglycerol Kinase Zeta; Diacylglycerol Kinase, Zeta 104kDa; Diglyceride Kinase Zeta; DAG Kinase Zeta; EC 2.7.1.107; DGK-ZETA; DAGK6; HDGKzeta; DAGK5
- Gene ID
- 8525
- UniProt ID
- Q13574
- Sequence Similarities
- Belongs to the eukaryotic diacylglycerol kinase family.
- Cellular Localization
- Nucleus
Cytoplasm, cytosol
Cell membrane
Cell projection, lamellipodium
- Post Translation Modifications
- Phosphorylation of the MARCKS homology domain by PKC reduces nuclear accumulation of DGK-zeta.
Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- NP_001099010.1; NP_001186195.1; NP_001186196.1; NP_001186197.1; NP_003637.2
- Function
- Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:9159104, 15544348, 18004883, 19744926, 22108654, 22627129, 23949095).
Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:9159104, 15544348, 18004883, 19744926, 22108654, 22627129, 23949095).
Also plays an important role in the biosynthesis of complex lipids (Probable).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "DGKZ"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC301 | Rabbit Anti-DGKZ Recombinant Antibody (VS13-YC301) | IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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