Rabbit Anti-DNM1 Recombinant Antibody (clone R09-6B8)
CAT#: VS3-XY3333
This is a recombinant rabbit antibody targeting the DNM1 (Dynamin 1), which plays a role in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells. It reacts with human, mouse and rat DNM1. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Gene Expression
Normal Tissue
Figure 1 High expression in cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Enterocytes - Microvilli Staining: Medium Intensity: Moderate Peripheral nerve/ganglion Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_9_5.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (A549, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106976-DNM1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DNM1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-6B8
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Developmental And Epileptic Encephalopathy 31A
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- DNM; DEE31; DEE31A; DEE31B; EIEE31
- Gene ID
- 1759
- UniProt ID
- Q05193
- Long Name
- Dynamin 1
- Cellular Localization
- Cytoplasm, Cytoskeleton
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q05193)
Modification sites at neXtProt (NX_Q05193)
Glycosylation from GlyGen (Q05193) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001005336.1; NP_001275666.1
- Function
- Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DNM1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3310z | Mouse Anti-DNM1 Recombinant Antibody (MOB-3310z) | WB, IP | Mouse IgG2a |
| MOB-2292CT | Recombinant Mouse anti-Human DNM1 Monoclonal antibody (6C5) | WB, ICC, IP | |
| MRO-1827-CN | Rabbit Anti-DNM1 Polyclonal Antibody (MRO-1827-CN) | WB, IHC | Rabbit IgG |
| VS3-XY587 | Mouse Anti-DNM1 Recombinant Antibody (clone 3G4B6) | ELISA, WB, IHC | Mouse IgG2a |
| VS7-HM826 | Mouse Anti-DNM1 Recombinant Antibody (clone CBL201HM) | WB, IHC-p, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3310z-F(E) | Recombinant Anti-Human DNM1 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3310z-S(P) | Recombinant Anti-Human DNM1 Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1024 | Hi-Affi™ Rabbit Anti-DNM1 Recombinant Antibody (clone DS1024AB) | ICC, IF, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2040 | Anti-DNM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2041 | Anti-Mouse DNM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2042 | Anti-Rat DNM1 Immunohistochemistry Kit | IHC |
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