Rabbit Anti-DNM1 Recombinant Antibody (clone R09-6B8) (CAT#: VS3-XY3333)
This is a recombinant rabbit antibody targeting the DNM1 (Dynamin 1), which plays a role in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells. It reacts with human, mouse and rat DNM1. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
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Normal Tissue
RNA Expression
Figure 1 High expression in cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_B_7_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_B_7_5.jpg
Figure 2 Colon
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Peripheral nerve/ganglion Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_7_3.jpg
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Peripheral nerve/ganglion Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_7_3.jpg
Figure 3 Kidney
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_9_5.jpg
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5920/155155_A_9_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (A549, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106976-DNM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106976-DNM1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DNM1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-6B8
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Developmental And Epileptic Encephalopathy 31A
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- DNM; DEE31; DEE31A; DEE31B; EIEE31
- Gene ID
- 1759
- UniProt ID
- Q05193
- Long Name
- Dynamin 1
- Cellular Localization
- Cytoplasm, Cytoskeleton
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q05193)
Modification sites at neXtProt (NX_Q05193)
Glycosylation from GlyGen (Q05193) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001005336.1; NP_001275666.1
- Function
- Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3310z | Mouse Anti-DNM1 Recombinant Antibody (MOB-3310z) | WB, IP | Mouse IgG2a |
| MRO-1827-CN | Rabbit Anti-DNM1 Polyclonal Antibody (MRO-1827-CN) | WB, IHC | Rabbit IgG |
| ZG-0264J | Mouse Anti-DNM1 Recombinant Antibody (ZG-0264J) | WB, IHC, ELISA | Mouse IgG |
| VS3-XY587 | Mouse Anti-DNM1 Recombinant Antibody (clone 3G4B6) | ELISA, WB, IHC | Mouse IgG2a |
| VS7-HM826 | Mouse Anti-DNM1 Recombinant Antibody (clone CBL201HM) | WB, IHC-p, IF, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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