Human Anti-DPEP3 Recombinant Antibody (clone SC-003/Tamrintamab)
CAT#: VS-0624-FY6
This product is a humanized IgG1, kappa antibody that was designed to target the human DPEP3 protein. This antibody effectively interacts with the dimerization interface of DPEP3 without inducing any structural modifications.
Gene Expression
Normal Tissue
Figure 1 High expression in testis
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_A_6_6_val_selected.jpg
Normal Tissue
Figure 2 Low expression in endometrium 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_B_6_3_val_selected.jpg
Normal Tissue
Figure 3 Testis
Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58607/131306_A_6_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141096-DPEP3
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Specifications
- Host Species
- Human
- Type
- Human IgG1 kappa
- Specificity
- Human DPEP3
- Species Reactivity
- Human
- Clone
- SC-003/Tamrintamab
- Applications
- Cytotoxicity
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Dipeptidase 3; EC 3.4.13.19; Testis Secretory Sperm-Binding Protein Li 211a; Metallopeptidase (Family M19); Membrane-Bound Dipeptidase 3; MBD3
- Gene ID
- 64180
- UniProt ID
- Q9H4B8
- Long Name
- Dipeptidase 3
- Sequence Similarities
- Belongs to the metallo-dependent hydrolases superfamily.
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn334 (NX_Q9H4B8 [NX_Q9H4B8-1])
Modification sites at PhosphoSitePlus (Q9H4B8)
Glycosylation from GlyGen (Q9H4B8) 1 site
- Protein Refseq
- NP_001123230.2; NP_001357127.1
- Function
- The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DPEP3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-240MZ | Mouse Anti-DPEP3 Recombinant Antibody (TAB-240MZ) | Cyt, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241MZ | Human Anti-DPEP3 Recombinant Antibody (TAB-241MZ) | Cyt, FuncS | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-240MZ-S(P) | Mouse Anti-DPEP3 Recombinant Antibody; scFv Fragment (TAB-240MZ-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241MZ-S(P) | Human Anti-DPEP3 Recombinant Antibody; scFv Fragment (TAB-241MZ-S(P)) | FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-240MZ-F(E) | Mouse Anti-DPEP3 Recombinant Antibody; Fab Fragment (TAB-240MZ-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241MZ-F(E) | Human Anti-DPEP3 Recombinant Antibody; Fab Fragment (TAB-241MZ-F(E)) | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC319 | Rabbit Anti-DPEP3 Recombinant Antibody (VS13-YC319) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC200 | Recombinant Anti-DPEP3 Vesicular Antibody, EV Displayed (VS-0425-YC200) | Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC103 | SmartAb™ Recombinant Anti-DPEP3 pH-dependent Antibody (VS-0825-YC103) | Cyt | Mouse IgG |
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