Human Anti-DPEP3 Recombinant Antibody (clone SC-003/Tamrintamab) (CAT#: VS-0624-FY6)
This product is a humanized IgG1, kappa antibody that was designed to target the human DPEP3 protein. This antibody effectively interacts with the dimerization interface of DPEP3 without inducing any structural modifications.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in testis
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_A_6_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_A_6_6_val_selected.jpg
Figure 2 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_B_6_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31870/135180_B_6_3_val_selected.jpg
Figure 3 Testis
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58607/131306_A_6_6.jpg
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58607/131306_A_6_6.jpg
Figure 4 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141096-DPEP3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141096-DPEP3
Specifications
- Host Species
- Human
- Type
- Human IgG1 kappa
- Specificity
- Human DPEP3
- Species Reactivity
- Human
- Clone
- SC-003/Tamrintamab
- Applications
- Cytotoxicity
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Dipeptidase 3; EC 3.4.13.19; Testis Secretory Sperm-Binding Protein Li 211a; Metallopeptidase (Family M19); Membrane-Bound Dipeptidase 3; MBD3
- Gene ID
- 64180
- UniProt ID
- Q9H4B8
- Long Name
- Dipeptidase 3
- Sequence Similarities
- Belongs to the metallo-dependent hydrolases superfamily.
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn334 (NX_Q9H4B8 [NX_Q9H4B8-1])
Modification sites at PhosphoSitePlus (Q9H4B8)
Glycosylation from GlyGen (Q9H4B8) 1 site
- Protein Refseq
- NP_001123230.2; NP_001357127.1
- Function
- The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
Humanized Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-240MZ | Mouse Anti-DPEP3 Recombinant Antibody (TAB-240MZ) | Cyt, FuncS | Mouse IgG |
| TAB-240MZ-S(P) | Mouse Anti-DPEP3 Recombinant Antibody; scFv Fragment (TAB-240MZ-S(P)) | FC | Mouse scFv |
| TAB-240MZ-F(E) | Mouse Anti-DPEP3 Recombinant Antibody; Fab Fragment (TAB-240MZ-F(E)) | FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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