Human Anti-dsDNA Recombinant Antibody (clone DIL-6) (CAT#: FAMAB-0014WJ)
This product is an IgG3, λ antibody with restricted antigen binding specificity.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 Binding of mAb RH-14 and DIL-6 to dsDNA attached to immunoassay plates was inhibited by dsDNA in the fluid phase.
Analyzed by competitive inhibition ELISA.
Ravirajan, C. T., Rahman, M. A., Papadaki, L., Griffiths, M. H., Kalsi, J., Martin, A. C., ... & Isenberg, D. A. (1998). Genetic, structural and functional properties of an IgG DNA‐binding monoclonal antibody from a lupus patient with nephritis. European journal of immunology, 28(1), 339-350.
ELISA
Figure 2 Binding of human anti-DNA IgG antibodies (Hu IgG) to α-actinin.
The pathogenic antibodies RH14 and B3 bound strongly to α-actinin, while the nonpathogenic antibody DIL-6 showed very weak binding to -actinin. Anti– -actinin binding was measured by solidphase enzyme-linked immunosorbent assay.
Ravirajan, C. T., Rahman, M. A., Papadaki, L., Griffiths, M. H., Kalsi, J., Martin, A. C., ... & Isenberg, D. A. (1998). Genetic, structural and functional properties of an IgG DNA‐binding monoclonal antibody from a lupus patient with nephritis. European journal of immunology, 28(1), 339-350.
Specifications
- Host Species
- Human
- Type
- Human IgG3, λ
- Specificity
- dsDNA
- Clone
- DIL-6
- Applications
- ELISA
- Related Disease
- Systemic lupus erythematosus
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The dsDNA antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Double-stranded DNA; dsDNA
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone DIL-6"
See other products for "dsDNA"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
IgM Antibody Products
Fab Antibody Products
ScFv Antibody Products
Autoantibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-077 | Mouse Anti-dsDNA Recombinant Antibody (clone 64M-5) | ELISA, WB, FuncS | Mouse IgG |
| FAMAB-0047WJ | Human Anti-dsDNA Recombinant Antibody (clone T14) | WB | Human IgG3 |
| FAMAB-0063WJ | Human Anti-dsDNA Recombinant Antibody (clone KSUG) | ELISA | Human IgG |
| FAMAB-0064WJ | Human Anti-dsDNA Recombinant Antibody (clone KSUN) | ELISA | Human IgM |
| FAMAB-0151JF | Mouse Anti-dsDNA Recombinant Antibody (clone G6-7) | WB, ELISA, IF, FC, FuncS | Mouse IgG2b |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0014WJ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: ELISA, WB, FC
Application: Neut, IHC, Activ, FuncS, IF, ELISA
Application: ELISA, WB, IF, FC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
