Human Anti-dsDNA Recombinant Antibody (clone RH-14) (CAT#: FAMAB-0013WJ)
This product is a IgG1, λ antibody binds to doule-stranded DNA, single-stranded DNA, histones and nucleosomes.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Binding of mAb RH-14 and DIL-6 to dsDNA attached to immunoassay plates was inhibited by dsDNA in the fluid phase.
Analyzed by competitive inhibition ELISA.
Ravirajan, C. T., Rahman, M. A., Papadaki, L., Griffiths, M. H., Kalsi, J., Martin, A. C., ... & Isenberg, D. A. (1998). Genetic, structural and functional properties of an IgG DNA‐binding monoclonal antibody from a lupus patient with nephritis. European journal of immunology, 28(1), 339-350.
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- dsDNA
- Clone
- RH-14
- Applications
- ELISA
- Related Disease
- Systemic lupus erythematosus
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The dsDNA antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Double-stranded DNA; dsDNA
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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PSBL-077 | Mouse Anti-dsDNA Recombinant Antibody (clone 64M-5); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
FAMAB-0092-YC-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone 165.60); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0093-YC-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone 163.72); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0108CQ-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone 17-45); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0109CQ-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone 2C10); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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