Human Anti-EBV gH/gL Vaccinal Antibody (VS-0625-XY12)

CAT#: VS-0625-XY12

This vaccinal antibody targets EBV gH/gL and is applicable for ELISA and neutralization (Neut) assays. It features Fc segment engineering to induce vaccine-like effects and enhance antiviral activity by boosting effector functions, thus combining diagnostic utility with improved therapeutic potential against EBV.

Specifications

  • Target
  • EBV gH/gL
  • Host Animal
  • Human
  • Applications
  • ELISA; Neut
  • Specificity
  • EBV gH/gL
  • Species Reactivity
  • EBV
  • Type
  • Human IgG
  • Purity
  • >95%, determined by SDS-PAGE
  • Purification
  • Protein A purified
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Target

  • Introduction
  • The Epstein-Barr virus (EBV) is a γ-herpesvirus that infects B cells and epithelial cells and that has been linked to malignancies in both cell types in vivo. EBV, like other herpesviruses, has three glycoproteins, glycoprotein B (gB), gH, and gL, that form the core membrane fusion machinery mediating viral penetration into the cell. The gH and gL proteins associate to form a heterodimeric complex, which is necessary for efficient membrane fusion and also implicated in direct binding to epithelial cell receptors required for viral entry.
  • Related Disease
  • Infectious mononucleosis
  • Alternative Names
  • Epstein-Barr virus glycoprotein H/glycoprotein L
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Secondary Antibody

Isotype Control

See other products for "EBV gH/gL"

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PABC-311 Recombinant Human Anti-EBV gH/gL Antibody (AMMO1) ELISA, BLI, Neut Human IgG
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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