Human Anti-EBV gH/gL Vaccinal Antibody (VS-0625-XY12)
CAT#: VS-0625-XY12
This vaccinal antibody targets EBV gH/gL and is applicable for ELISA and neutralization (Neut) assays. It features Fc segment engineering to induce vaccine-like effects and enhance antiviral activity by boosting effector functions, thus combining diagnostic utility with improved therapeutic potential against EBV.
Specifications
- Target
- EBV gH/gL
- Host Animal
- Human
- Applications
- ELISA; Neut
- Specificity
- EBV gH/gL
- Species Reactivity
- EBV
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- The Epstein-Barr virus (EBV) is a γ-herpesvirus that infects B cells and epithelial cells and that has been linked to malignancies in both cell types in vivo. EBV, like other herpesviruses, has three glycoproteins, glycoprotein B (gB), gH, and gL, that form the core membrane fusion machinery mediating viral penetration into the cell. The gH and gL proteins associate to form a heterodimeric complex, which is necessary for efficient membrane fusion and also implicated in direct binding to epithelial cell receptors required for viral entry.
- Related Disease
- Infectious mononucleosis
- Alternative Names
- Epstein-Barr virus glycoprotein H/glycoprotein L
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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CAT | Product Name | Application | Type |
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PFBC-311 | Recombinant Human Anti-EBV gH/gL Antibody Fab Fragment (AMMO1) | ELISA, Neut | Human Fab |
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CAT | Product Name | Application | Type |
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PSBC-419 | Recombinant Mouse Anti-EBV gH/gL Antibody scFv Fragment (CL40) | ELISA, FC, Neut | Mouse scFv |
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