Mouse Anti-Mycobacterium tuberculosis HSP65 Antibody (VS-0925-XY42)

CAT#: VS-0925-XY42

Mycobacterium tuberculosis HSP65 antibodies (duplicate) offer consistent detection, aiding immunoprecipitation of HSP65 complexes and research on its cross-reactivity with host proteins. Reliable for both basic science and translational tuberculosis studies.

Specifications

  • Host Animal
  • Mouse
  • Applications
  • WB, ELISA
  • Specificity
  • Mycobacterium tuberculosis HSP65
  • Target
  • Mycobacterium tuberculosis HSP65
  • Species Reactivity
  • Bacteria
  • Type
  • Mouse IgG2a
  • Purification
  • Protein A Purified
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.2
  • Preservative
  • 0.1% sodium azide
  • Storage
  • This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.

Target

  • Introduction
  • Mycobacterium tuberculosis HSP65 is the same heat shock protein as described above, serving as a key chaperone in Mycobacterium tuberculosis. It ensures proper protein folding and stability under host-induced stress, which is vital for bacterial persistence in intracellular environments like macrophages. Its high conservation and immunogenicity make it a target for both tuberculosis diagnosis and vaccine development. In diagnostics, the detection of HSP65-specific immune responses aids in identifying infections, while in vaccines, it aims to elicit protective immunity against Mycobacterium tuberculosis. However, its similarity to human HSP60 necessitates consideration of potential autoimmune risks, guiding the design of safe and effective HSP65-based interventions.
  • Alternative Names
  • M. tuberculosis Heat Shock Protein 65, Mtb HSP65
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VS-0925-XY41 Mouse Anti-Mycobacterium tuberculosis HSP65 Antibody (VS-0925-XY41) WB, ELISA Mouse IgG2a
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