Mouse Anti-ERC2 Recombinant Antibody (VS-0326-YC1179)
CAT#: VS-0326-YC1179
This product is an anti-ERC2 antibody panel that contains two antibodies targeting ERC2. ERC2 (also known as CAST) is a large scaffold protein localized to the presynaptic active zone of neurons. It coordinates the organization of the cytomatrix, facilitating the docking and priming of synaptic vesicles. ERC2 signaling is essential for the precise temporal and spatial control of neurotransmitter release, directly impacting synaptic strength and plasticity. Two monoclonal antibodies, VS-0326-YC67 and VS-0326-YC68, directed against ERC2 were used for in vitro assays including Immunohistochemistry (IHC) and Immunoprecipitation (IP).
Gene Expression
Normal Tissue
Figure 1 High expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73739/165854_B_7_5_selected.jpg
Normal Tissue
Figure 2 Low expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73739/165854_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73739/165854_B_7_5.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73739/165854_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73739/165854_A_9_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HAP1, HUVEC TERT2, Karpas-707, SH-SY5Y, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187672-ERC2
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| Sub Cat | Type | Clone | Species Reactivity | Applications | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0326-YC67 | Mouse IgG2b | ER67 | Human | IHC | IHC (1/20-1/100) | ||||||
| VS-0326-YC68 | Mouse IgG1 | ER68 | Human, Mouse | IP | IP (1/100-1/200) |
More Infomation
Specifications
- Host Species
- Mouse
- Specificity
- ERC2
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "ERC2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1182 | Hi-Affi™ Rabbit Anti-ERC2 Recombinant Antibody (clone DS1182AB) | WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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