Mouse Anti-ETS1 Recombinant Antibody (VS3-CJ658)
CAT#: VS3-CJ658
This product is a mouse antibody that recognizes human ETS1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/63230/1151_D9_1_selected.jpg
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Specifications
- Immunogen
- Recombinant protein of human ETS1
- Host Species
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human ETS1
- Species Reactivity
- Human
- Applications
- WB, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:500), Flow Cytometry (1:25).
Target
- Alternative Names
- p54; ETS-1; EWSR2; c-ets-1
- Gene ID
- 2113
- UniProt ID
- P14921
- Sequence Similarities
- Belongs to the ETS family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity.
Ubiquitinated; which induces proteasomal degradation.
Phosphorylation at Ser-251, Ser-282 and Ser-285 by CaMK2/CaMKII in response to calcium signaling decreases affinity for DNA: an increasing number of phosphoserines causes DNA-binding to become progressively weaker.
- Protein Refseq
- NP_001137292.1; NP_001155894.1; NP_001317380.1
- Function
- Transcription factor (PubMed:10698492, PubMed:11909962).
Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371).
May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371).
May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
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Recommended Dilution Buffer
- CAT
- Product Name
See other products for "ETS1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3991z | Mouse Anti-ETS1 Recombinant Antibody (clone 25F12) | ELISA, FC, IF, IHC, WB | Mouse IgG1 |
| MRO-0557-CN | Rabbit Anti-ETS1 Recombinant Antibody (clone JM92-32) | WB, IHC, FC | Rabbit IgG |
| VS3-XY654 | Mouse Anti-ETS1 Recombinant Antibody (clone 10D2) | ELISA, WB, IHC | Mouse IgG1 |
| VS7-HM913 | Mouse Anti-ETS1 Recombinant Antibody (clone CBL263HM) | WB, IHC-p, IF, ICC, FCM, ELISA | Mouse IgG |
| VS7-HM914 | Mouse Anti-ETS1 Recombinant Antibody (clone CBL264HM) | WB, IHC-p, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1207 | Hi-Affi™ Rabbit Anti-ETS1 Recombinant Antibody (clone DS1207AB) | FC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY787 | Anti-ETS1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2375 | Anti-Human ETS1 Immunohistochemistry Kit | IHC |
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