Human Anti-EV71 Recombinant Antibody (clone 38-1-10A)

CAT#: VS-0723-CJ1

This human anti-EV71 antibody 38-1-10A binds close to the virus icosahedral threefold axis with the heavy and light chains positioned roughly equidistant from the axis, shielding an unusually large area (1400 Å2) of virus surface. This antibody has been tested for use in flow cytometry, ELISA, immunoprecipitation, neutralization and inhibition assays.

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Enterovirus 71 (EV71)
  • Species Reactivity
  • EV71
  • Clone
  • 38-1-10A
  • Applications
  • FC, ELISA, IP, Neut, Inhib
  • Conjugate
  • Unconjugated
  • Related Disease
  • Hand, foot and mouth disease

Product Property

  • Purification
  • Protein A purified
  • Purity
  • >95%
  • Buffer
  • PBS
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Antibody 38-1-10A was used for binding to the EV71 virion in a competitive ELISA. For immunoprecipitation, the beads-antibody complex was incubated with pre-cleared EV71-containing supernatants. Antibody 38-1-10A neutralized virus at picomolar level. Antibody 38-1-10A conferred full protection from lethality by EV71 in the infected mice at a prophylactic dose of 0.4 mg/kg.

Target

  • Alternative Names
  • Enterovirus 71 (EV71)
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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