AbPlus™ Anti-FBL Magnetic Beads (VS-0724-YC408) (CAT#: VS-0724-YC408)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-FBL specific antibody

• Target
• FBL

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human Fibrillarin/FBL.

• Target Species
• Human, Mouse, Rat

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

• Alternative Names
• Fibrillarin; 34 KDa Nucleolar Scleroderma Antigen; Histone-Glutamine Methyltransferase; FLRN; RNA, U3 Small Nucleolar Interacting Protein 1; RRNA 2-O-Methyltransferase Fibrillarin; 34-KD Nucleolar Scleroderma Antigen; EC 2.1.1.37;

• Gene ID
• 2091

• UniProt ID
• P22087

Select a product category from the dropdown menu below to view related products.